ID A0A399FZB3_9ACTN Unreviewed; 1046 AA.
AC A0A399FZB3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=DUF3427 domain-containing protein {ECO:0000313|EMBL:UOE19568.1};
DE SubName: Full=Helicase {ECO:0000313|EMBL:RII01688.1};
GN ORFNames=NI17_023145 {ECO:0000313|EMBL:UOE19568.1}, NI17_15415
GN {ECO:0000313|EMBL:RII01688.1};
OS Thermobifida halotolerans.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Nocardiopsaceae; Thermobifida.
OX NCBI_TaxID=483545 {ECO:0000313|EMBL:RII01688.1};
RN [1] {ECO:0000313|EMBL:RII01688.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44931 {ECO:0000313|EMBL:RII01688.1};
RA Toth A., Tancsics T.A., Farkas T., Papp P., Olasz F., Balint B.,
RA Herczeg R., Nagy I., Baka E., Kukolya J.;
RT "De novo genome project of the cellulose decomposer Thermobifida
RT halotolerans type strain.";
RL Submitted (OCT-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:UOE19568.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DSM 44931 {ECO:0000313|EMBL:UOE19568.1};
RA Nagy I., Horvath B., Kukolya J., Nagy I., Orsini M.;
RT "De novo genome project of the cellulose decomposer Thermobifida
RT halotolerans type strain.";
RL Submitted (OCT-2020) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JRUV01000268; RII01688.1; -; Genomic_DNA.
DR EMBL; CP063196; UOE19568.1; -; Genomic_DNA.
DR RefSeq; WP_068687913.1; NZ_LIZN01000001.1.
DR AlphaFoldDB; A0A399FZB3; -.
DR Proteomes; UP000265719; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd18032; DEXHc_RE_I_III_res; 1.
DR CDD; cd09203; PLDc_N_DEXD_b1; 1.
DR CDD; cd18799; SF2_C_EcoAI-like; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR021835; DUF3427.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR025202; PLD-like_dom.
DR PANTHER; PTHR47962; ATP-DEPENDENT HELICASE LHR-RELATED-RELATED; 1.
DR PANTHER; PTHR47962:SF7; MITOCHONDRIAL ATP-DEPENDENT HELICASE IRC3-RELATED; 1.
DR Pfam; PF11907; DUF3427; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF13091; PLDc_2; 1.
DR Pfam; PF04851; ResIII; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:RII01688.1};
KW Helicase {ECO:0000313|EMBL:RII01688.1};
KW Hydrolase {ECO:0000313|EMBL:RII01688.1};
KW Nucleotide-binding {ECO:0000313|EMBL:RII01688.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000265719}.
FT DOMAIN 332..473
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 547..700
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 1046 AA; 116991 MW; A43738C8A0B7601F CRC64;
MPRPPHDPRP AAGLYESLLT DRLEQYVEEL STRGWRVVRG KVGEQSAPHV LARYVADRVE
RALDGLAPEE RVAAANRILD VLGPPDGSGA GSERVLDGPR QLLALTDREE IPLTQRPATP
LSEAALLTNA PDDPGLGSEL RRELATADRI DLLCAFIKWH GLRWLEQPLR AARARGVPIR
VITTTYLGAT ERRALDRLVT EFGAEVKINY ETRSTRLHAK AWLFWRDSGY HTAYVGSSNL
SRAALLDGLE WNVRLSAVAT PAVLRKFAAT FDSYWSDPAF EDYLPHRDTA RLDEALAVAG
GRTSPGGHVT LSGLEVRPFP HQRDMLEQLA AERLVHDRHR NLLVAATGTG KTVMAALDYR
RLRHAHGDAP TLLFVAHRRE ILEHARRTYQ EVLNDADFGE LLFGAERPRA WRHVFAGIQA
LSARGLADLP SDHFDVVVVD EFHHASASTY RRLLDHVRPR ELLGLTATPE RADGVNVQDE
FFGGRVAAEL RLWEALDSDL LSPFHYFGIS DSTDLSAVTW KRGGYDRDEL SALFTGNDAR
ARLVLRAVRD KVADPNAMRA LGFCVSVAHA EYMAAFFRKA GLNARALSGR SGEDERREVL
AGLRGGTVRV VFSVDLFNEG VDIPDVDTLL LLRPTSSATV FLQQLGRGLR RAEGKAVLTV
LDLIGQHRRE FRFDHQFRAL TNLTRKRLVE GVEQGFPRLP SGCQIVLDPR ARETVLANIR
RQIDVTAPRL AAEIRSHGTP RLAEYLAGSG RDAGEVYRSG RSWTGLLRRA GLLPDSAPDG
ETALLRRVSA FLHVDDPVRA DAYTRLLADD APAYADLDER DRVFARMLFF SLWPDGGRFP
TYQRGFDRLR DHPRVRDELR QVVAHGLAQA RHAPVPLLLD TAPGLPLAVH ASYSREEILP
ALGQSGLGGA HRRVPANFRE GVKWCPNIAT DALLVTLEKD ERDFSPQTRY RDYALNERLF
HWESQNRTSE TSTTGLRYQR HREEGSHVLL FVRHRKTTDF GTVQPWMLLG PADYVEHRGS
NPMGIVWRLH HEMPTDVWSY AAATAS
//
