ID   A0A399SGN0_9BACT        Unreviewed;       346 AA.
AC   A0A399SGN0;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=NAD(P)-dependent alcohol dehydrogenase {ECO:0000313|EMBL:RIJ42368.1};
GN   ORFNames=D1627_00400 {ECO:0000313|EMBL:RIJ42368.1};
OS   Pontibacter oryzae.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC   Pontibacter.
OX   NCBI_TaxID=2304593 {ECO:0000313|EMBL:RIJ42368.1, ECO:0000313|Proteomes:UP000266005};
RN   [1] {ECO:0000313|Proteomes:UP000266005}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KIRAN {ECO:0000313|Proteomes:UP000266005};
RA   Seo T.;
RT   "Mucilaginibacter sp. MYSH2.";
RL   Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947,
CC         ECO:0000256|RuleBase:RU361277};
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00008072, ECO:0000256|RuleBase:RU361277}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RIJ42368.1}.
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DR   EMBL; QWGE01000001; RIJ42368.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A399SGN0; -.
DR   OrthoDB; 9806940at2; -.
DR   Proteomes; UP000266005; Unassembled WGS sequence.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd05283; CAD1; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR047109; CAD-like.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR42683; ALDEHYDE REDUCTASE; 1.
DR   PANTHER; PTHR42683:SF85; CINNAMYL ALCOHOL DEHYDROGENASE 6-RELATED; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   3: Inferred from homology;
KW   Metal-binding {ECO:0000256|RuleBase:RU361277};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Zinc {ECO:0000256|RuleBase:RU361277}.
FT   DOMAIN          14..341
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   346 AA;  38272 MW;  52AAB28D742F9C73 CRC64;
     MIQSKGYAVK EASAPLGDFS FERREVGAKD VLIDILYCGV CHSDLHQVRN EWGNSIYPMV
     PGHEIVGRVK QVGSHVSRFK EGDLAGIGCF VDSCRHCRSC EDGLEQYCEN NLVMTYNGYD
     KDGSLTYGGY SNKIVVDEKY TLKVPENLEL SHVAPLLCAG ITTYSPIMEW KIGQGHRVGI
     VGLGGLGHMA VKIAASRGAD VTVLSTSPGK EQDARDLGAH NFAITKNEET MKELAETFDF
     IIDTVSAPHD YNMYLNLLKR DGTMILLGAP PAPAEVMAAN LLFKRRRLVG SLIGGIQETQ
     EMLDYCAEHN IVSDVEVIPM DYINEAYERM EKGDVKYRFV IDMSTL
//