ID A0A3A1P0R0_9SPHN Unreviewed; 675 AA.
AC A0A3A1P0R0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:RIV80969.1};
GN Name=mrdA {ECO:0000313|EMBL:RIV80969.1};
GN ORFNames=D2V17_18955 {ECO:0000313|EMBL:RIV80969.1};
OS Aurantiacibacter xanthus.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Erythrobacteraceae; Aurantiacibacter.
OX NCBI_TaxID=1784712 {ECO:0000313|EMBL:RIV80969.1, ECO:0000313|Proteomes:UP000265366};
RN [1] {ECO:0000313|EMBL:RIV80969.1, ECO:0000313|Proteomes:UP000265366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCTCC AB 2015396 {ECO:0000313|EMBL:RIV80969.1,
RC ECO:0000313|Proteomes:UP000265366};
RA Fang C., Wu Y.-H., Sun C., Wang H., Cheng H., Meng F.-X., Wang C.-S.,
RA Xu X.-W.;
RT "Erythrobacter zhengii sp.nov., a bacterium isolated from deep-sea
RT sediment.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RIV80969.1}.
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DR EMBL; QXFM01000140; RIV80969.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3A1P0R0; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000265366; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000265366}.
FT DOMAIN 61..232
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 265..585
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
FT REGION 642..675
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 675 AA; 73612 MW; 9B85FF5C36FE779F CRC64;
MEPRLSSNSL KETFDRRSFV LGAVQGGVGL LLAARMGYIA VAENEKYKME AESNRVNLSL
IPPRRGWILD RNGSPLASNR SDFRVDIIPE RLHDRDATVD LLAKVLAFDD LERKDLIERI
ENASSFQVVP VASGLDFEKY AALTVRLPEL PGVLPQQSYA RYYPTGTSVG HLIGYVGAPS
REEYVLEPKP LLLTPGFKMG KNGIEKQFEQ ELRGVPGARR VEVTATGRRV RDLETREDVP
GNPIRLTIDG PLQDYAARRI GLESGSVVVI DCLTGDLLCM ASMPSFDPNS FSDGIGRVEY
SMLSENDRVP LRNKVLQGLY PPGSTVKPMV AMAFLEAGLS PDASVSCNGG LRVGNRVFHC
WNRRGHGRVD MAKGIYQSCD VYFYHFAQQL GMNVISDMAR RCGLGQEFPL PVASQFYGTV
PDPAWKLKKY GREWQAFDTV NATIGQGYML FNPLQLAVYS ARIATGRTVM PRLILDGKTP
KFSSMNFHGD HVQVIQNAMS DVINGPGTAG RARLPIDDVL MAGKTGTAQV VSLAISNGKS
GPWKYRDHGL FISFAPFNNP RYACAVVIEH GGGSGSAYPI ARDVMTFLFD PAKALDALHG
FEKQWGGTAQ QRLAQSYAAY AAAAGVDLPP APPPFKLAEK VDAEARAATA EPDTPVTDAL
VPREDPVASA NGNLT
//
