ID A0A3A2Z343_9EURO Unreviewed; 618 AA.
AC A0A3A2Z343;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 22-FEB-2023, entry version 15.
DE RecName: Full=RNA-binding protein VTS1 {ECO:0000256|ARBA:ARBA00024136};
GN ORFNames=PHISCL_10171 {ECO:0000313|EMBL:RJE17492.1};
OS Aspergillus sclerotialis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Polypaecilum.
OX NCBI_TaxID=2070753 {ECO:0000313|EMBL:RJE17492.1, ECO:0000313|Proteomes:UP000266188};
RN [1] {ECO:0000313|Proteomes:UP000266188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 366.77 {ECO:0000313|Proteomes:UP000266188};
RA Tafer H., Lopandic K.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Monomer. Binds to RNA. {ECO:0000256|ARBA:ARBA00024046}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, P-body
CC {ECO:0000256|ARBA:ARBA00004201}. Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- SIMILARITY: Belongs to the VTS1 family.
CC {ECO:0000256|ARBA:ARBA00007325}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RJE17492.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MVGC01000895; RJE17492.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3A2Z343; -.
DR STRING; 2070753.A0A3A2Z343; -.
DR Proteomes; UP000266188; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0000932; C:P-body; IEA:UniProtKB-SubCell.
DR GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR GO; GO:0043488; P:regulation of mRNA stability; IEA:InterPro.
DR CDD; cd09556; SAM_VTS1_fungal; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR037635; VTS1_SAM.
DR PANTHER; PTHR12515:SF5; PROTEIN SMAUG; 1.
DR PANTHER; PTHR12515; STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED; 1.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000266188};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 550..608
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 182..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 225..328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 344..369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 398..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 452..479
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 517..549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..26
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..269
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 283..312
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..428
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 519..540
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 618 AA; 66547 MW; B5D519A7D5FF9078 CRC64;
MASHIIGNRN STPEASKSSL RPPTSARALG SHQLRASADM SGFPAPLSAR SIRPSSEVYY
NQQSQGQNND DALDRASQQW LADIEQYETT LEEMAAATLD QDFKDELSAI EQWFRVLSEA
ERTAALYALL QQTTQVQIRF FIQVLQQMAK SHPMSGLLSP ANFGEKDAMS NRMNDAMSKL
NVDNSRNSMG RPPPSPGAKR NTGLDSSTIN AMFPDAAAAI ARKKAEFTQQ TGNAPPSNRN
SAVFGDRSSF IPPTISAPDN NNDSIGQPPA SPWTHRGAET QPPISRPKSS SGQQPMGQFS
QPSASGLRSP LGGQTVTMPP PDVEAPLLSP YNVGNASWAS MTNTPMTATF GGQQHQPPQQ
QQQQGTQADM VANATAMKLA ALSTVNNRIA LDDARKYRRA RSNDGQGKSS NANANQSMPQ
NLNSPGLQGS NLVAGQLLNA QQLAALQAQQ QAAMAGRRSR PTSPGIAMQG GSLGPMGFTS
PQNNGFLTAY DPNSHLMGNG LGAFGIGQFG LGGHEGYLSD HSEVTRGRSP RGRRGSSKPP
EDPTDPNLLK DIPAWLRSLR LHKYTDHLKD LKWTELVELD DKALEERGVN ALGARNKMLK
VFEQVKEAKS EGKLDSIL
//
