ID   A0A3A2ZKP7_9EURO        Unreviewed;       350 AA.
AC   A0A3A2ZKP7;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:RJE22883.1};
GN   ORFNames=PHISCL_04779 {ECO:0000313|EMBL:RJE22883.1};
OS   Aspergillus sclerotialis.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Polypaecilum.
OX   NCBI_TaxID=2070753 {ECO:0000313|EMBL:RJE22883.1, ECO:0000313|Proteomes:UP000266188};
RN   [1] {ECO:0000313|Proteomes:UP000266188}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 366.77 {ECO:0000313|Proteomes:UP000266188};
RA   Tafer H., Lopandic K.;
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. {ECO:0000256|ARBA:ARBA00008072}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RJE22883.1}.
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DR   EMBL; MVGC01000146; RJE22883.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3A2ZKP7; -.
DR   STRING; 2070753.A0A3A2ZKP7; -.
DR   Proteomes; UP000266188; Unassembled WGS sequence.
DR   GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:InterPro.
DR   CDD; cd08249; enoyl_reductase_like; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   InterPro; IPR047122; Trans-enoyl_RdTase-like.
DR   PANTHER; PTHR45348; HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG); 1.
DR   PANTHER; PTHR45348:SF2; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000266188}.
FT   DOMAIN          12..348
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   350 AA;  37709 MW;  8671E3D4855F1197 CRC64;
     MSQKALILKE IGTPLVLTDR PIPVPGENEL LVKITSAGLN PHDHRSRDWG LFVADLPYIP
     AHDIAGKVLA VGPGDGAAKF HVGEHVYAQA RMPLDQVFID FHGLQEFALV DVRLAAKIAD
     TGLTDDEAAT IPVNVASLFV ALFHHTGLGL PIPGTEEAKA TDLSDEAILI IGAGSNCGRA
     GVEFARMAGF GTIIAHAGPS NEEELRAMGA THFVNRHASN VLDQIRFIVG DDLLYALDVV
     NFGPQQGLGI AALSNSKKGT LVTLLPTDGE LDISEIGPKE AGFDRRMTFG KMAIIPEFAP
     EFWNRISQWL KEGRISPGKF KVMEGLDADK VNEVLDLYRD GRGVKVHIHP
//