ID A0A3A2ZR36_9EURO Unreviewed; 1072 AA.
AC A0A3A2ZR36;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 22-FEB-2023, entry version 15.
DE SubName: Full=Exportin-1 {ECO:0000313|EMBL:RJE25619.1};
GN ORFNames=PHISCL_02012 {ECO:0000313|EMBL:RJE25619.1};
OS Aspergillus sclerotialis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Polypaecilum.
OX NCBI_TaxID=2070753 {ECO:0000313|EMBL:RJE25619.1, ECO:0000313|Proteomes:UP000266188};
RN [1] {ECO:0000313|Proteomes:UP000266188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 366.77 {ECO:0000313|Proteomes:UP000266188};
RA Tafer H., Lopandic K.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex. Involved in pre-tRNA
CC splicing, probably by affecting the interaction of pre-tRNA with
CC splicing endonuclease. {ECO:0000256|ARBA:ARBA00025147}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RJE25619.1}.
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DR EMBL; MVGC01000042; RJE25619.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3A2ZR36; -.
DR STRING; 2070753.A0A3A2ZR36; -.
DR Proteomes; UP000266188; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR041123; CRM1_repeat.
DR InterPro; IPR041235; Exp1_repeat_2.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR045065; XPO1/5.
DR InterPro; IPR014877; XPO1_C_dom.
DR InterPro; IPR040485; XPO1_repeat_3.
DR PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR PANTHER; PTHR11223:SF2; EXPORTIN-1; 1.
DR Pfam; PF08767; CRM1_C; 1.
DR Pfam; PF18777; CRM1_repeat; 1.
DR Pfam; PF18784; CRM1_repeat_2; 1.
DR Pfam; PF18787; CRM1_repeat_3; 1.
DR Pfam; PF03810; IBN_N; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SMART; SM01102; CRM1_C; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000266188};
KW Transport {ECO:0000256|ARBA:ARBA00022448};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 26..92
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
SQ SEQUENCE 1072 AA; 123006 MW; 3B5F8C555818ED99 CRC64;
MSVSIQELDN TVQAFYEGKG DLQKQAQQTL TEFKQNPDAW LIVGNILQES SYPQTKYLAL
QVLDDVIMTR WKVLPREQCL GIRNFIVNFI IENSKSEESL RSERAFLNKL NLVLVSILKQ
EWPHNWPTFI NEIISACHNS LSICENNMAI LRLLSEEVFD FSQDQMTSVK ARNLKTSMTQ
EFSSIFQLCS EVLSSANQPS LVKATLETLL RFLNWIPLGY IFETPIINTL LTRFLDVPEF
RNVTLKCLTE IGGLQIGAPY NYDERLVHMF TETLTTVSKT IPLSMDLRQT YAKSNSRDQE
FVLNLALFLC SFFSAHLNVI EKLPNRDYLS HAHFYLIRIS QIDDREVFKI CLEYWTRLVQ
ELYEEMQQLP ITDLNPLVSM GVSGMSNGGA PHPSTLANYP LRKHKYEDVL SNLRTVMIEK
MVRPEEVLIV ENDEGEIVRE FVKESDTIQL YKTIRECLVY LTHLDVVDTE NIMIEKLAKQ
VDGSEWSWAN CNTLCWAIGS ISGAMNEETE KRFLVTVIKD LLGLTEMKRG KDNKAVVASN
IMYIVGQYPR FLKAHWKFLK TVVNKLFEFM HETHEGVQDM ACDTFIKIAN KCRRHFVALQ
PGENEPFIEE IVRNMRKITC DLSPLQVHTF YEACGYMISA QGQKGLQDRL TENLMSLPNS
AWDAIIAQAN QNPSILQDGE TIKIIGNIMK TNVAACSSIG TYFYSQIGRI YHDMLSMFRA
SSQLISDAVA HDGNIATKTP KVRGLRTIKK EILKLIDTYV QKADNLEMVN ATMVPPLLEA
VLIDYNRNVP DAREAEVLNV MTTIIHKLHN LMDDKVPAIM ESVFECTLDM ISKDFHEYPE
HRVQFFKLLQ AINLYCFPAL LKLDTAQFKF VIDSCMWASK HDNREVENTG LAMCLELMNN
MAETDPQTSS VFFRQFYVPI LQDVLFVLTD SDHKAGFKSQ AMLLSRMFYF IESGKIQGPI
YSPEQAPPGT SDKEFLQEYV ANLLQNAFKN LQEVQIKQFV LGLFMLNDDF IKFKTHLRDF
LISLKEFAGD NAELYAEERE QALRDAKAAE RDRAMKVGGL LKPSEMEQED EL
//
