ID A0A3A2ZRW3_9EURO Unreviewed; 337 AA.
AC A0A3A2ZRW3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Carboxyphosphonoenolpyruvate phosphonomutase {ECO:0000313|EMBL:RJE25063.1};
GN ORFNames=PHISCL_02598 {ECO:0000313|EMBL:RJE25063.1};
OS Aspergillus sclerotialis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Polypaecilum.
OX NCBI_TaxID=2070753 {ECO:0000313|EMBL:RJE25063.1, ECO:0000313|Proteomes:UP000266188};
RN [1] {ECO:0000313|Proteomes:UP000266188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 366.77 {ECO:0000313|Proteomes:UP000266188};
RA Tafer H., Lopandic K.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate +
CC succinate; Xref=Rhea:RHEA:16809, ChEBI:CHEBI:15361,
CC ChEBI:CHEBI:30031, ChEBI:CHEBI:57429; EC=4.1.3.30;
CC Evidence={ECO:0000256|ARBA:ARBA00001050};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RJE25063.1}.
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DR EMBL; MVGC01000059; RJE25063.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3A2ZRW3; -.
DR STRING; 2070753.A0A3A2ZRW3; -.
DR Proteomes; UP000266188; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd00377; ICL_PEPM; 1.
DR Gene3D; 3.20.20.60; Phosphoenolpyruvate-binding domains; 1.
DR InterPro; IPR039556; ICL/PEPM.
DR InterPro; IPR018523; Isocitrate_lyase_ph_CS.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR PANTHER; PTHR42905; PHOSPHOENOLPYRUVATE CARBOXYLASE; 1.
DR PANTHER; PTHR42905:SF2; PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN; 1.
DR Pfam; PF13714; PEP_mutase; 1.
DR SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
DR PROSITE; PS00161; ISOCITRATE_LYASE; 1.
PE 4: Predicted;
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Pyruvate {ECO:0000313|EMBL:RJE25063.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000266188}.
SQ SEQUENCE 337 AA; 36289 MW; C93572E81AB42017 CRC64;
MKVEESSLKT DVVTTITVEK NGVYEVNGVK HEPSVSVQML TGASKLRRQL LESKDLIVCP
GVYDGLSARI AIQLGFKALY MTGAGTTASR LGMADLGLAQ LHDMRTNAEM IASLDPFGPP
LIADMDTGYG GPLMVAKSVQ QYIQAGVAGF HIEDQVQNKR CGHLAGKKVV SLDEYLIRIR
AAKRTKDRLH SDIVLIARTD ALQQHGYDEC IRRLKAAQDL GADVGLLEGF TSKEQARQAV
QDLAPWPLLL NMVENGAGPV ITTQEAQEMG FRIMIFSFAS LAPAYLGIKA ALERLKTHGI
VGTPEGVGPK KLFEVCGLME SVYIDTTAGG SGFVNGV
//
