ID A0A3A2ZYM9_9EURO Unreviewed; 470 AA.
AC A0A3A2ZYM9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 13-SEP-2023, entry version 11.
DE SubName: Full=UDP-glucose 6-dehydrogenase {ECO:0000313|EMBL:RJE26487.1};
GN ORFNames=PHISCL_01197 {ECO:0000313|EMBL:RJE26487.1};
OS Aspergillus sclerotialis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Polypaecilum.
OX NCBI_TaxID=2070753 {ECO:0000313|EMBL:RJE26487.1, ECO:0000313|Proteomes:UP000266188};
RN [1] {ECO:0000313|Proteomes:UP000266188}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 366.77 {ECO:0000313|Proteomes:UP000266188};
RA Tafer H., Lopandic K.;
RL Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the UDP-glucose/GDP-mannose dehydrogenase
CC family. {ECO:0000256|PIRNR:PIRNR000124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RJE26487.1}.
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DR EMBL; MVGC01000021; RJE26487.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3A2ZYM9; -.
DR STRING; 2070753.A0A3A2ZYM9; -.
DR Proteomes; UP000266188; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR017476; UDP-Glc/GDP-Man.
DR InterPro; IPR014027; UDP-Glc/GDP-Man_DH_C.
DR InterPro; IPR036220; UDP-Glc/GDP-Man_DH_C_sf.
DR InterPro; IPR014026; UDP-Glc/GDP-Man_DH_dimer.
DR InterPro; IPR001732; UDP-Glc/GDP-Man_DH_N.
DR InterPro; IPR028359; UDP_ManNAc/GlcNAc_DH.
DR NCBIfam; TIGR03026; NDP-sugDHase; 1.
DR PANTHER; PTHR43491; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR PANTHER; PTHR43491:SF2; UDP-N-ACETYL-D-MANNOSAMINE DEHYDROGENASE; 1.
DR Pfam; PF00984; UDPG_MGDP_dh; 1.
DR Pfam; PF03720; UDPG_MGDP_dh_C; 1.
DR Pfam; PF03721; UDPG_MGDP_dh_N; 1.
DR PIRSF; PIRSF500136; UDP_ManNAc_DH; 1.
DR PIRSF; PIRSF000124; UDPglc_GDPman_dh; 1.
DR SMART; SM00984; UDPG_MGDP_dh_C; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF52413; UDP-glucose/GDP-mannose dehydrogenase C-terminal domain; 1.
PE 3: Inferred from homology;
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000266188}.
FT DOMAIN 372..467
FT /note="UDP-glucose/GDP-mannose dehydrogenase C-terminal"
FT /evidence="ECO:0000259|SMART:SM00984"
SQ SEQUENCE 470 AA; 52398 MW; AC464F933F3F9D6F CRC64;
MNIAQDYSSS VPNKDYAQDN WRKINADWPV DTPPPEIGDA YYSERASRAS QFPVSEAERP
VVAVIGVGYI DIQLVTAFAA HFDVIAFDVS KRRHTDVVAE VDQCLPVRFT SAAEDIACAT
HFLIAVPTTL RPDHRLDTSH LRSAIYSVAL WARTGATVVV ESSVAVGMTR NFLGQMMRVR
QLKAGMSPEV RSYHIVSAAM LMTLQRVDSG RLKPALQDIL KIISGLDEIT PGSLDSIDKL
YSKVFRTIIR VSKPEVAEMT KFYENCQRMV GIAYANEMAD ACVAHGIDAF EVCSAAATKP
FGYIPYTPGL GVGGHCIPIN PYYLLSNCEF PILQAATENT KGRPRRLGDR VVKSFLYSRR
GEEVWNRRLQ ILVVGVAFKK GQSDTRNSPA VALIQHLLDR WEAEVTFADP LVAQEKLPYV
LRLDERTEWN KESLDSFNII IVTMEQVGLD ISSLDNLDEA EVVSYVRVFK
//
