ID A0A3A3FXM9_9BURK Unreviewed; 348 AA.
AC A0A3A3FXM9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN ORFNames=D3878_04330 {ECO:0000313|EMBL:RJG00907.1};
OS Noviherbaspirillum sedimenti.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Oxalobacteraceae; Noviherbaspirillum.
OX NCBI_TaxID=2320865 {ECO:0000313|EMBL:RJG00907.1, ECO:0000313|Proteomes:UP000266327};
RN [1] {ECO:0000313|Proteomes:UP000266327}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K1S02-23 {ECO:0000313|Proteomes:UP000266327};
RA Zhu H.;
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RJG00907.1}.
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DR EMBL; QYUQ01000002; RJG00907.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3A3FXM9; -.
DR OrthoDB; 9811073at2; -.
DR Proteomes; UP000266327; Unassembled WGS sequence.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR004622; DNA_pol_HolB.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00678; holB; 1.
DR PANTHER; PTHR11669:SF8; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR Pfam; PF13177; DNA_pol3_delta2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000266327};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REGION 86..113
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..113
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 348 AA; 38518 MW; 6758459F0F848A1D CRC64;
MNIDLFPWQE SSWRQLQSLR ARLPHAILFH GPAGIGKTLF AERFAQSLLC QAPDAAGQAC
GQCASCGWFS QYNHPDYRRV RPEVLEEAEG AAGEDEEEGG DAKKGGKSAK APSKDIRIDQ
IRALADFMNI STHRQGKRVV LLYPAEALNS AAANALLKTL EEPPPETVFL LISNSLDRLL
PTILSRCRKF ALTLPPFDQA LAWLKAQGVD DADSWLAEQG GAPLAAQELG QSGNREAMEE
FLAYLARPGV DAALKTAERL QKTPPAQQVE WLQRWLYDLF SVKLSGKIRY YPRYKKELAA
LGAQVGVPAL LQALKAAGER RAIAEHPLSP KLFIEDMLLD YSRLYSSY
//
