ID A0A3A4A7R7_9ACTN Unreviewed; 674 AA.
AC A0A3A4A7R7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Acetoacetate--CoA ligase {ECO:0000313|EMBL:RJL22057.1};
DE EC=6.2.1.16 {ECO:0000313|EMBL:RJL22057.1};
GN ORFNames=D5H75_36275 {ECO:0000313|EMBL:RJL22057.1};
OS Bailinhaonella thermotolerans.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Bailinhaonella.
OX NCBI_TaxID=1070861 {ECO:0000313|EMBL:RJL22057.1, ECO:0000313|Proteomes:UP000265768};
RN [1] {ECO:0000313|EMBL:RJL22057.1, ECO:0000313|Proteomes:UP000265768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM 75507 {ECO:0000313|EMBL:RJL22057.1,
RC ECO:0000313|Proteomes:UP000265768};
RA Tang S., Feng Y.;
RT "YIM 75507 draft genome.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RJL22057.1}.
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DR EMBL; QZEY01000023; RJL22057.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3A4A7R7; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000265768; Unassembled WGS sequence.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:RJL22057.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000265768}.
FT DOMAIN 61..115
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 125..490
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..23
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 674 AA; 73093 MW; 3A51C84198160FDE CRC64;
MPELPEPPAL PENPGPPRTP AFSADPEPLY SPGPDAREGT QLGRFLDWLA AERGLRFDDW
AALHAWSVSD LAGFWSALWE FFQIKAAKPY DEVVSGREMP GAVWFRGALL NYAEHMFGEP
EDAGRVAVLG RSQTRPDVTL TFGELREQVA RARAGLRRLG VGRGDRVVAY LPNIPETLVA
FLATASLGAV WASCAPEFGA PGVIDRFGQV EPTVLLVVDG YRYGERHVDR RGEVAALREG
LPTVRHVVHV PYGGNAVPDA VTWDDLLDGD PGPLEFEHVP FDHPLFVLFT SGTTGKPKAI
VHGHGGILIE HFKNGGLSWD LKPGDRMLWF STTAWMLWNA LVSALLLRAS IVMLDGDPAY
PDIAGQWRTA GETGATLVGV SPAYLMTCRK QGVRPAEVAD LSRLNQLGVA GSPLPVEGYH
WVHEQFGGRV LLNVGCGGTD LCSAIIQGSP LQPVWAGEIS GPCLGVDAKA YDPDGNVVVG
ELGELVITAP MPSMPVGFWG DEDGSRYRAA YFEDYPGVWR HGDWVRFLPT GSAIITGRSD
ATLNRGGVRL GTAEFYRVVE ELPEIDDSLI VHLEDRDGGL GELLLFVRPA DGVDLDDALR
DRLRLALRTA LSPRHVPDRI IAVASVPRNR TGKKVEVPVK RILLGEDPDK VASRESLTDP
SSLDAFVALA GDRA
//
