ID A0A3A4AYT8_9ACTN Unreviewed; 1364 AA.
AC A0A3A4AYT8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Amino acid adenylation domain-containing protein {ECO:0000313|EMBL:RJL31017.1};
GN ORFNames=D5H75_21230 {ECO:0000313|EMBL:RJL31017.1};
OS Bailinhaonella thermotolerans.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Bailinhaonella.
OX NCBI_TaxID=1070861 {ECO:0000313|EMBL:RJL31017.1, ECO:0000313|Proteomes:UP000265768};
RN [1] {ECO:0000313|EMBL:RJL31017.1, ECO:0000313|Proteomes:UP000265768}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM 75507 {ECO:0000313|EMBL:RJL31017.1,
RC ECO:0000313|Proteomes:UP000265768};
RA Tang S., Feng Y.;
RT "YIM 75507 draft genome.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RJL31017.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QZEY01000008; RJL31017.1; -; Genomic_DNA.
DR OrthoDB; 2472181at2; -.
DR Proteomes; UP000265768; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:UniProt.
DR GO; GO:1901566; P:organonitrogen compound biosynthetic process; IEA:UniProt.
DR CDD; cd05930; A_NRPS; 1.
DR CDD; cd05235; SDR_e1; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.980; -; 2.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 1.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR013120; Far_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR010080; Thioester_reductase-like_dom.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR NCBIfam; TIGR01746; Thioester-redct; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR Pfam; PF00668; Condensation; 1.
DR Pfam; PF07993; NAD_binding_4; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000265768}.
FT DOMAIN 896..971
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 509..534
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1364 AA; 143595 MW; 967A0B79362F281D CRC64;
MTAAQAGIWA GQRLDPASPA YNAAEYVEIP GAVDPWLFES AVRLALTEAE ALHARFDGEA
QVLDVGADWP FHRLDVPDRE AAEEWMRADL AVPADLARGP VFTQALLTAP DRVFWYQRIH
HIAADGYSFS LIARRVAATY SALLRNEHPG PGFGPLGPVV REDAAYRDSE RFARDRDFWV
ERCAGRAEPV TLAPPGPASH PAIRRTAPLP ADLAATRGRA SWGDLVIAAV AALLHRETGA
GEVTLGLPVM GRMGSAALRV PCMAMNIVPL RIPVDPAGTP RALALRVAAE LRATRPHHRY
RYEDLRRDLG LVGGDRRLFG PVVNIMPFDD ELRFGDARGV VHRLSAGPVE DLSVGVRPDG
AGGLRLDLEA NPAAYRDEDL AAVERGLLDL LADPDGPVTR PVVLSGGPLR EPARPVLDLI
AARPAGATAL VHAGRAVTYG ELRAAAGDFA GRLAGAGVRP GDLVALRHPR GVEAVTAILG
TLAAGAAYLP LDPDGPASRE RDILADARPS LLSTPGGLRP LPDPADPLDP DRGTPDAGDG
LAYVIYTSGS TGTPKGVAVG RRALANFVAG ARERYAITER DMVLQFAPLH FDASVEEIFV
TLCSGGTLVI RTGEMLESIP RLLAACDEAG VTVLDLPTAY WHELAYAVST GAARLPGRLR
LVIIGGEAVL PERVARWHEA VGGAVTLLNT YGPTEGTVVA TAAELTPGDP EITIGAPLPG
VRVAVAGGEL WLLGAGLARG YLGNPALTAE RFPAVAALGG ERAYRTGDRV RPRPDGRLVY
LGRMDDEFKI SGHRVDPAEV ENALLSHPSV REAAVVGRTG LGGAKRLVAH VVAEDGLEVA
ALREHARERL PAAVVPSAYV LAERLPRTPS GKIDRSALRE TAAEAAGTPA AGDAGVAANG
LERLILRIWA EVLGPGAYGP SDDFFELGGQ SLQTIQVANR LGVELGREVP AATVFRHPTP
AALAHALGPR PAEPYAGGSR AREPYVEDAE LPGGLVPPAV RAARPAGRVL LTGATGFVGA
HLLAELAATG ARVVCPVRAG DERAARERIG AALGGYGLRV PPDLVEAVPA DLADPSDLAG
LPGRAGEVDA VFHAAATVSL LRPYGSVRRA NVIATRELLR AALAGGVPFH HVSTVAVGAW
REDFVGPHDG LRDGYQQSKW AAEHLVRQAG ERGLPVAAYR LGRVVGPTAT GYVNPQDIVW
RILRTAVEAG AIPDLPVAEP WTPVDHVARV LVRLALGGAT GVFNVVPAEP VRFADVAAWT
REYGYRLDPL PLPAWRRRLE SSGIDPATLA FFDLHAAPAA DPVPADVIPA DAIPADRLAR
ELPGAAFPEI GRDAVHAYLD HCVKTGLLPH PSPGAGETSR DGAR
//
