ID A0A3A4KU62_9NOCA Unreviewed; 504 AA.
AC A0A3A4KU62;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=D5S18_01355 {ECO:0000313|EMBL:RJO79936.1};
OS Nocardia panacis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Nocardia.
OX NCBI_TaxID=2340916 {ECO:0000313|EMBL:RJO79936.1, ECO:0000313|Proteomes:UP000266677};
RN [1] {ECO:0000313|EMBL:RJO79936.1, ECO:0000313|Proteomes:UP000266677}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YIM PH 21724 {ECO:0000313|EMBL:RJO79936.1,
RC ECO:0000313|Proteomes:UP000266677};
RA Miao C.;
RT "YIM PH21274 draft genome.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RJO79936.1}.
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DR EMBL; QZFU01000006; RJO79936.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3A4KU62; -.
DR OrthoDB; 9767435at2; -.
DR Proteomes; UP000266677; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004673; F:protein histidine kinase activity; IEA:InterPro.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.450.280; GAF domain; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR038424; H_kinase_PdtaS_GAF_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR022066; PdtaS_GAF.
DR InterPro; IPR011495; Sig_transdc_His_kin_sub2_dim/P.
DR InterPro; IPR011102; Sig_transdc_His_kinase_HWE.
DR PANTHER; PTHR41523:SF7; ETHYLENE RESPONSE SENSOR PROTEIN; 1.
DR PANTHER; PTHR41523; TWO-COMPONENT SYSTEM SENSOR PROTEIN; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07568; HisKA_2; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF12282; PdtaS_GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00911; HWE_HK; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000266677};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 305..500
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 504 AA; 54215 MW; 29ED01670B3140B1 CRC64;
MATLSELLAE HTDLPGVAVD HLQRVVGDWQ LLADLSFADL LLWVGAGPVA DGAEVVCVAQ
CRPTTAATVH VEDLVGSTAS KDDHPQVFEA LLTGKIVRSD SEVEAGGVYH PHPVHATREA
IPVRCGDDII AVLSRDTDVQ RSRVRSTLEI AYVACADDLC QMISEGTFPT TEDRAATHSS
PRAGDGFIRI DTEGIVVYAS PNALSAYHRM GLQSDLAGQD LAVTTRSLIT DPFDAQEVVG
DIQAALAGRT GRRMEVEARG ATVLLRTLVL RPHGALAGAA VLVRDVTEVK RRDRALLSKD
ATIREIHHRV KNNLQTVAAL LRLQARRTEN EEAQVALTES VRRVTSIASV HEMLSMSVDE
EVDLDEVVDR LLPIMADVAT VHTARIKVRR AGSLGVFSAE RATPLVMVLT ELVQNAIEHA
FDPGQNGTVT IRSERSARWL DVIISDDGRG LPPGFSLESS DRLGLQIVRT LVTAELGGSI
GLHPGADIGT DAVLRVPLGR RSGR
//
