ID A0A3A5J9D5_9GAMM Unreviewed; 398 AA.
AC A0A3A5J9D5;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Formaldehyde dehydrogenase, glutathione-independent {ECO:0000313|EMBL:RJS94830.1};
DE EC=1.2.1.46 {ECO:0000313|EMBL:RJS94830.1};
GN Name=fdhA {ECO:0000313|EMBL:RJS94830.1};
GN ORFNames=D3260_03430 {ECO:0000313|EMBL:RJS94830.1};
OS Salinisphaera sp. Q1T1-3.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Salinisphaerales;
OC Salinisphaeraceae; Salinisphaera.
OX NCBI_TaxID=2321229 {ECO:0000313|EMBL:RJS94830.1, ECO:0000313|Proteomes:UP000269039};
RN [1] {ECO:0000313|EMBL:RJS94830.1, ECO:0000313|Proteomes:UP000269039}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Q1T1-3 {ECO:0000313|EMBL:RJS94830.1,
RC ECO:0000313|Proteomes:UP000269039};
RA Zayas Rivera J., Montalvo Rodriguez R.;
RT "Draft Genome of Salinisphaera endophytica, a Novel Species of the
RT Salinisphaera Genus Isolated as an Endophyte of Avicennia germinans, at the
RT Solar Salterns of Cabo Rojo.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RJS94830.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; QZWD01000002; RJS94830.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3A5J9D5; -.
DR OrthoDB; 9773078at2; -.
DR Proteomes; UP000269039; Unassembled WGS sequence.
DR GO; GO:0018467; F:formaldehyde dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:UniProt.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08282; PFDH_like; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR007698; AlaDH/PNT_NAD(H)-bd.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR014184; HCHO_DH_non_GSH.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR NCBIfam; TIGR02819; fdhA_non_GSH; 1.
DR PANTHER; PTHR42813:SF3; GLUTATHIONE-INDEPENDENT FORMALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF01262; AlaDh_PNT_C; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:RJS94830.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000269039}.
FT DOMAIN 36..145
FT /note="Alcohol dehydrogenase-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08240"
FT DOMAIN 183..251
FT /note="Alanine dehydrogenase/pyridine nucleotide
FT transhydrogenase NAD(H)-binding"
FT /evidence="ECO:0000259|Pfam:PF01262"
SQ SEQUENCE 398 AA; 42076 MW; 8E5A2D5DEC4861EF CRC64;
MSSPSNRGVV FRGKGEVAVE SIDFPQLALG RRTCEHGVIL KVVTTNICGS DQHMVRGRTT
APTGMVLGHE ITGEVIECGR DVEFINVGDI VSVPFNVACG RCRNCKRGDT HICLNVNDDR
PGGAYGYVDM GGWVGGQAEY VMVPYADFQL LVFPDKEQAM EKILDLTMLS DIFPTGFHGC
VTAGVGPGST VYIAGAGPVG LAAACSAQLL GAACVIVGDM NPQRLDQARS FGCETIDLRQ
DASMSELIES VLGVPEVDCA VDAVGFEANC HGHNHSHEAP ATVLNATMEI VQAGGRVGIP
GLYVTEDPGA TSDDAKHGNL SMKFGLGWAK AMSFHTGQTP AMRYHRQLMQ AILHDKAAIG
KAVNVQTISL DEAPQGYAAF DDGAAKKFVI DPHSQIAA
//
