ID A0A3A6R5J9_9VIBR Unreviewed; 249 AA.
AC A0A3A6R5J9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Sulfate transporter CysZ {ECO:0000256|HAMAP-Rule:MF_00468};
GN Name=cysZ {ECO:0000256|HAMAP-Rule:MF_00468,
GN ECO:0000313|EMBL:RJX71659.1};
GN ORFNames=DZ860_09875 {ECO:0000313|EMBL:RJX71659.1};
OS Vibrio sinensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=2302434 {ECO:0000313|EMBL:RJX71659.1, ECO:0000313|Proteomes:UP000273252};
RN [1] {ECO:0000313|EMBL:RJX71659.1, ECO:0000313|Proteomes:UP000273252}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BEI233 {ECO:0000313|EMBL:RJX71659.1,
RC ECO:0000313|Proteomes:UP000273252};
RA Li Y.;
RT "Vibrio isolated from the Eastern China Marginal Seas.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: High affinity, high specificity proton-dependent sulfate
CC transporter, which mediates sulfate uptake. Provides the sulfur source
CC for the cysteine synthesis pathway. {ECO:0000256|HAMAP-Rule:MF_00468}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC Rule:MF_00468}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC Rule:MF_00468}.
CC -!- SIMILARITY: Belongs to the CysZ family. {ECO:0000256|HAMAP-
CC Rule:MF_00468}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RJX71659.1}.
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DR EMBL; QVMU01000007; RJX71659.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3A6R5J9; -.
DR OrthoDB; 5292355at2; -.
DR Proteomes; UP000273252; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015116; F:sulfate transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR GO; GO:0019344; P:cysteine biosynthetic process; IEA:UniProtKB-UniRule.
DR GO; GO:0000103; P:sulfate assimilation; IEA:InterPro.
DR HAMAP; MF_00468; CysZ; 1.
DR InterPro; IPR022985; Sulfate_CysZ.
DR PANTHER; PTHR37468; SULFATE TRANSPORTER CYSZ; 1.
DR PANTHER; PTHR37468:SF1; SULFATE TRANSPORTER CYSZ; 1.
DR Pfam; PF07264; EI24; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|HAMAP-Rule:MF_00468};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519, ECO:0000256|HAMAP-
KW Rule:MF_00468};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_00468}; Cysteine biosynthesis {ECO:0000256|HAMAP-Rule:MF_00468};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_00468};
KW Sulfate transport {ECO:0000256|ARBA:ARBA00023032, ECO:0000256|HAMAP-
KW Rule:MF_00468};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_00468};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_00468};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_00468}.
FT TRANSMEM 29..49
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00468"
FT TRANSMEM 69..90
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00468"
FT TRANSMEM 141..161
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00468"
FT TRANSMEM 207..240
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00468"
SQ SEQUENCE 249 AA; 28312 MW; 2862CC5C900D8C56 CRC64;
MNTHIQPRSG FSYFFYGLQI ALTPGIRRFV LMPLLANILL VGGALFYLFS HMDQWIQQLL
GQIPDFLSWL SYVLWPLIAI TILATFSYFF STLANFIAAP FNGLLAEKVE MHLTGKKIND
DGLLDIVKDV PRILGREWRK IRYVLPKAIG LFLLLLIPGL GQTLGPVLWF IFTAWMLAIQ
YCDYPFDNHK ISFQDMRHNL KQKQTTAYGF GALVAVFTTI PILNLVVMPI AVCGATALWV
AEFKHKHTS
//
