ID   A0A3A8B405_9RHOB        Unreviewed;       251 AA.
AC   A0A3A8B405;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Uroporphyrinogen-III synthase {ECO:0000313|EMBL:RKF16301.1};
GN   ORFNames=D6850_01705 {ECO:0000313|EMBL:RKF16301.1};
OS   Roseovarius spongiae.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Roseovarius.
OX   NCBI_TaxID=2320272 {ECO:0000313|EMBL:RKF16301.1, ECO:0000313|Proteomes:UP000281128};
RN   [1] {ECO:0000313|EMBL:RKF16301.1, ECO:0000313|Proteomes:UP000281128}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HN-E21 {ECO:0000313|EMBL:RKF16301.1,
RC   ECO:0000313|Proteomes:UP000281128};
RA   Zhuang L., Luo L.;
RT   "Roseovarius spongiae sp. nov., isolated from a marine sponge.";
RL   Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RKF16301.1}.
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DR   EMBL; RAPE01000001; RKF16301.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3A8B405; -.
DR   OrthoDB; 7204250at2; -.
DR   Proteomes; UP000281128; Unassembled WGS sequence.
DR   GO; GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:InterPro.
DR   GO; GO:0033014; P:tetrapyrrole biosynthetic process; IEA:InterPro.
DR   CDD; cd06578; HemD; 1.
DR   Gene3D; 3.40.50.10090; -; 1.
DR   InterPro; IPR036108; 4pyrrol_syn_uPrphyn_synt_sf.
DR   InterPro; IPR003754; 4pyrrol_synth_uPrphyn_synth.
DR   Pfam; PF02602; HEM4; 1.
DR   SUPFAM; SSF69618; HemD-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000281128}.
FT   DOMAIN          30..230
FT                   /note="Tetrapyrrole biosynthesis uroporphyrinogen III
FT                   synthase"
FT                   /evidence="ECO:0000259|Pfam:PF02602"
SQ   SEQUENCE   251 AA;  26430 MW;  A55BE202E2FD8335 CRC64;
     MQTTAHPSRR PIVLVTRPEP EGAAFAAELA ARHGDAVRLI RAPIMEIVRD ADLPDLKGIE
     TLVFTSRNGV RAYAAATARR EIPCYAVGDA TAEAARAEGL SAISAEGDAR ALVALMIADR
     VRGPVMQLHG THRAGDIPGA LRAAGIEARA VPIYDQRARP LSPEARRALR GDAPVVLPLF
     SPRSAELVIN DTPPTCPLVA AVISEAARDR LPDPLARDAI VAARPDGPAM HDAVTQAIAT
     AKRLEGAKGT Q
//