ID A0A3A9EKS7_9FIRM Unreviewed; 290 AA.
AC A0A3A9EKS7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=MurR/RpiR family transcriptional regulator {ECO:0000313|EMBL:RKJ39941.1};
GN ORFNames=D7X94_09930 {ECO:0000313|EMBL:RKJ39941.1};
OS Acutalibacter sp. 1XD8-33.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Acutalibacter.
OX NCBI_TaxID=2320081 {ECO:0000313|EMBL:RKJ39941.1, ECO:0000313|Proteomes:UP000270929};
RN [1] {ECO:0000313|EMBL:RKJ39941.1, ECO:0000313|Proteomes:UP000270929}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1XD8-33 {ECO:0000313|EMBL:RKJ39941.1,
RC ECO:0000313|Proteomes:UP000270929};
RA Liu C.;
RT "Murine metabolic-syndrome-specific gut microbial biobank.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKJ39941.1}.
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DR EMBL; RAZF01000013; RKJ39941.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3A9EKS7; -.
DR OrthoDB; 2930at2; -.
DR Proteomes; UP000270929; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:1901135; P:carbohydrate derivative metabolic process; IEA:InterPro.
DR CDD; cd05013; SIS_RpiR; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR000281; HTH_RpiR.
DR InterPro; IPR047640; RpiR-like.
DR InterPro; IPR035472; RpiR-like_SIS.
DR InterPro; IPR001347; SIS_dom.
DR InterPro; IPR046348; SIS_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR30514; GLUCOKINASE; 1.
DR PANTHER; PTHR30514:SF18; RPIR-FAMILY TRANSCRIPTIONAL REGULATOR; 1.
DR Pfam; PF01418; HTH_6; 1.
DR Pfam; PF01380; SIS; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51071; HTH_RPIR; 1.
DR PROSITE; PS51464; SIS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000270929};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 135..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 3..79
FT /note="HTH rpiR-type"
FT /evidence="ECO:0000259|PROSITE:PS51071"
FT DOMAIN 125..264
FT /note="SIS"
FT /evidence="ECO:0000259|PROSITE:PS51464"
SQ SEQUENCE 290 AA; 32286 MW; 9FF42DA972E2069B CRC64;
MNNQLSARIQ DSSRGFSKSQ RAIARYLQEH PEEVAFMTAS RLGATVGVSE STVVRFATEI
GYSGYPAMQQ AVQEMIRNKL TSFQRLEMTS RNFPQERLLD AVLGQDIDIL RHTRESRDEE
AFYRAVDALV GVRRVFVLGA GSSLALATFL AHYLRLVFDT VLLIEATSEA SIYQQMVRAR
AEDAIIAISF PRYSKKAAKA LQYASSRGMT AIAITDSRLS PVAESASHVL LAHSDMVSFV
DSLVGPLSLI NALIVTVAIR KKQEVAETLR QIESIWDEYG VYEKVEERNA
//
