ID   A0A3A9GB22_9FIRM        Unreviewed;       656 AA.
AC   A0A3A9GB22;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=ATP-dependent endonuclease {ECO:0000313|EMBL:RKJ61910.1};
GN   ORFNames=D7Y06_18850 {ECO:0000313|EMBL:RKJ61910.1};
OS   Roseburia sp. 1XD42-69.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX   NCBI_TaxID=2320088 {ECO:0000313|EMBL:RKJ61910.1, ECO:0000313|Proteomes:UP000279120};
RN   [1] {ECO:0000313|EMBL:RKJ61910.1, ECO:0000313|Proteomes:UP000279120}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1XD42-69 {ECO:0000313|EMBL:RKJ61910.1,
RC   ECO:0000313|Proteomes:UP000279120};
RA   Liu C.;
RT   "Murine metabolic-syndrome-specific gut microbial biobank.";
RL   Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RKJ61910.1}.
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DR   EMBL; RAZG01000056; RKJ61910.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3A9GB22; -.
DR   OrthoDB; 308933at2; -.
DR   Proteomes; UP000279120; Unassembled WGS sequence.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   CDD; cd01026; TOPRIM_OLD; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR041685; AAA_15.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR034139; TOPRIM_OLD.
DR   PANTHER; PTHR43581; ATP/GTP PHOSPHATASE; 1.
DR   PANTHER; PTHR43581:SF2; ATP_GTP PHOSPHATASE; 1.
DR   Pfam; PF13175; AAA_15; 1.
DR   Pfam; PF20469; OLD-like_TOPRIM; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Endonuclease {ECO:0000313|EMBL:RKJ61910.1};
KW   Hydrolase {ECO:0000313|EMBL:RKJ61910.1};
KW   Nuclease {ECO:0000313|EMBL:RKJ61910.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000279120}.
FT   DOMAIN          1..396
FT                   /note="AAA"
FT                   /evidence="ECO:0000259|Pfam:PF13175"
FT   DOMAIN          445..518
FT                   /note="OLD protein-like TOPRIM"
FT                   /evidence="ECO:0000259|Pfam:PF20469"
SQ   SEQUENCE   656 AA;  74504 MW;  B397D7B9C3814D10 CRC64;
     MRLSNIKIKN YRLLIDAELK VDDSITLIVG RNNTAKTSCA ELIDKVLKNR ALSYDDYPLK
     KRKYAYILLA QFMRNKISFE NLCKIFPLTA IDFYVDYSLD DPNMNLGALS PFIIDVDVDS
     TMAIIHAEYS IKISEDSLRI MFETCFFENN KFVCKPEDVR DVSIANFAKI FGLNIYAINP
     KNENDNQLKT QKELVDLFPF YSIPAERMLG ENGDHNINSL GTLISGYFSA DIENLDPKVS
     EEVKILRKTV EDANIKLQRQ SSELLGTIVN RAVGFGYPNA EELQLGVNTR LQIDDQIKDK
     TELTYTSVEM GESLPSSHNG LGYKNLIKIE FMLADFAEKI KLGNLACIPL LFIEEPESHM
     HPQMQHTFAG YLEKFLREIS DVHIQTFLTS HSAHIANNIE FSKIRYAQKT IKGVIYKNLN
     TFAKDNEGNM DFINKYLTLS RCDLFFADKV IFVEGASERL LLPDMIEKCD RDGLFNAKKY
     KLPSQYYALI EIGGAYANKF IPFVNFLGIP CLILTDIDSM EDGRTKAIVS KGKTTSNATL
     KWWMRKVKGL PENGTSTIDL AEIIALTDAQ KTIGKCHIEF QVKEQGLCGR SLEEAVKNVN
     RNHYGLKGSI TEEDLEFTDK SKTDFALNLV CANPNYIIPK YIKDGLVWLN EQNVLV
//