ID   A0A3A9GCE9_9FIRM        Unreviewed;       511 AA.
AC   A0A3A9GCE9;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Nitrite/sulfite reductase {ECO:0000313|EMBL:RKJ64425.1};
GN   ORFNames=D7Y06_12335 {ECO:0000313|EMBL:RKJ64425.1};
OS   Roseburia sp. 1XD42-69.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX   NCBI_TaxID=2320088 {ECO:0000313|EMBL:RKJ64425.1, ECO:0000313|Proteomes:UP000279120};
RN   [1] {ECO:0000313|EMBL:RKJ64425.1, ECO:0000313|Proteomes:UP000279120}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1XD42-69 {ECO:0000313|EMBL:RKJ64425.1,
RC   ECO:0000313|Proteomes:UP000279120};
RA   Liu C.;
RT   "Murine metabolic-syndrome-specific gut microbial biobank.";
RL   Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RKJ64425.1}.
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DR   EMBL; RAZG01000022; RKJ64425.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3A9GCE9; -.
DR   OrthoDB; 9803707at2; -.
DR   Proteomes; UP000279120; Unassembled WGS sequence.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.413.10; Sulfite Reductase Hemoprotein, domain 1; 2.
DR   Gene3D; 3.90.480.10; Sulfite Reductase Hemoprotein;Domain 2; 1.
DR   InterPro; IPR005117; NiRdtase/SiRdtase_haem-b_fer.
DR   InterPro; IPR036136; Nit/Sulf_reduc_fer-like_dom_sf.
DR   InterPro; IPR006067; NO2/SO3_Rdtase_4Fe4S_dom.
DR   InterPro; IPR045854; NO2/SO3_Rdtase_4Fe4S_sf.
DR   InterPro; IPR006066; NO2/SO3_Rdtase_FeS/sirohaem_BS.
DR   PANTHER; PTHR32439:SF9; BLR3264 PROTEIN; 1.
DR   PANTHER; PTHR32439; FERREDOXIN--NITRITE REDUCTASE, CHLOROPLASTIC; 1.
DR   Pfam; PF01077; NIR_SIR; 1.
DR   Pfam; PF03460; NIR_SIR_ferr; 1.
DR   PRINTS; PR00397; SIROHAEM.
DR   SUPFAM; SSF56014; Nitrite and sulphite reductase 4Fe-4S domain-like; 2.
DR   SUPFAM; SSF55124; Nitrite/Sulfite reductase N-terminal domain-like; 2.
PE   4: Predicted;
KW   Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00022617};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022617};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000279120}.
FT   DOMAIN          45..106
FT                   /note="Nitrite/Sulfite reductase ferredoxin-like"
FT                   /evidence="ECO:0000259|Pfam:PF03460"
FT   DOMAIN          119..268
FT                   /note="Nitrite/sulphite reductase 4Fe-4S"
FT                   /evidence="ECO:0000259|Pfam:PF01077"
SQ   SEQUENCE   511 AA;  56664 MW;  ACC60D3D04803503 CRC64;
     MDKNYAEEFR SDLAEFREKT KLFYEGKLSV PEYKGFSGGF GSYAQRGAKC GMLRLRLYGG
     RVTKDYLKFV IDSIDKYHID RVHLTTCQTI QLHNLSGETI CSLIEEAWDH GIITRGGGGD
     FPRNVMMTPL AGVTKEEAFD VSPYAKEAAD YLLSFIKAVK LPRKLKVCFS STKENFPHAT
     FRDLGFVACE DGTFDVYSAG GLGNNPKMGV KVADHVAPEK ILYYIKAMVD TFTAYGNYEN
     RGRARTRYMQ DTLGADGYKK AYQEKLEETL KNENLEINVT VPSIKKSGDG NLNHQRAFPQ
     KQEGLYAVSY HPIGGNPTPD MLHKILDAIL PMEDVEIRLT PEEGMYFINC TAKEGEKLIA
     LTDDGAETLF ETSVACIGNS ICQVGARDSQ SLLNDCVKAV RPLKFPDGVL PKIHISGCPS
     SCSAHQIGSI GFRGGVKQTP EGPKAAFAMY VNGSDIQGEE RFGEDAGVLT VEDIPRFFVA
     LGKEISGAKE TFETWYPKNR EKFMEIVGQF A
//