ID A0A3A9GHE2_9FIRM Unreviewed; 331 AA.
AC A0A3A9GHE2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=UDP-N-acetylglucosamine 4,6-dehydratase (Inverting) {ECO:0000313|EMBL:RKJ60326.1};
DE EC=4.2.1.115 {ECO:0000313|EMBL:RKJ60326.1};
GN Name=pseB {ECO:0000313|EMBL:RKJ60326.1};
GN ORFNames=D7Y06_24195 {ECO:0000313|EMBL:RKJ60326.1};
OS Roseburia sp. 1XD42-69.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=2320088 {ECO:0000313|EMBL:RKJ60326.1, ECO:0000313|Proteomes:UP000279120};
RN [1] {ECO:0000313|EMBL:RKJ60326.1, ECO:0000313|Proteomes:UP000279120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1XD42-69 {ECO:0000313|EMBL:RKJ60326.1,
RC ECO:0000313|Proteomes:UP000279120};
RA Liu C.;
RT "Murine metabolic-syndrome-specific gut microbial biobank.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000256|ARBA:ARBA00007430}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKJ60326.1}.
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DR EMBL; RAZG01000142; RKJ60326.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3A9GHE2; -.
DR OrthoDB; 9803111at2; -.
DR Proteomes; UP000279120; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003869; Polysac_CapD-like.
DR InterPro; IPR020025; PseB.
DR NCBIfam; TIGR03589; PseB; 1.
DR PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR PANTHER; PTHR43318:SF2; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE (INVERTING); 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:RKJ60326.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000279120}.
FT DOMAIN 7..284
FT /note="Polysaccharide biosynthesis protein CapD-like"
FT /evidence="ECO:0000259|Pfam:PF02719"
SQ SEQUENCE 331 AA; 37385 MW; AE6879DC996EAA2F CRC64;
MLNNKTILIT GGTGSFGKKF LEKIFAEYEP KKVIIYSRDE FKQSVMKTDY MDKVDMSRVR
FFIGDVRDKE RLNRAFEGVD YVIHAAAMKQ VPTCEYNPME AIKTNVHGAQ NVIDAALDCG
VKKVVALSTD KAVNPINLYG GTKLVSDKLF IAANAYRGNN HDTVFSVVRY GNVAGSRGSV
IPIWQKIIDE GGKTLGVTDM RMTRFWITLD QGVDLVFKAL HESKGGETYI SKIPSFHIGD
LARAMLPDCN IDEFGIREGE KLHEVMVTKD DSLLTFEYEK HYIIYPHFEW WDFNAGFTEG
GVKVPDGFEY NSGTNTQWLG TEELKEALKR I
//
