ID A0A3A9GHP2_9FIRM Unreviewed; 467 AA.
AC A0A3A9GHP2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=ATP-binding protein {ECO:0000313|EMBL:RKJ61628.1};
GN ORFNames=D7Y06_19845 {ECO:0000313|EMBL:RKJ61628.1};
OS Roseburia sp. 1XD42-69.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=2320088 {ECO:0000313|EMBL:RKJ61628.1, ECO:0000313|Proteomes:UP000279120};
RN [1] {ECO:0000313|EMBL:RKJ61628.1, ECO:0000313|Proteomes:UP000279120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1XD42-69 {ECO:0000313|EMBL:RKJ61628.1,
RC ECO:0000313|Proteomes:UP000279120};
RA Liu C.;
RT "Murine metabolic-syndrome-specific gut microbial biobank.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKJ61628.1}.
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DR EMBL; RAZG01000063; RKJ61628.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3A9GHP2; -.
DR OrthoDB; 9778566at2; -.
DR Proteomes; UP000279120; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16935; HATPase_AgrC-ComD-like; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR032834; NatK_C.
DR InterPro; IPR016120; Sig_transdc_His_kin_SpoOB.
DR PANTHER; PTHR40448; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR PANTHER; PTHR40448:SF1; TWO-COMPONENT SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF14501; HATPase_c_5; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55890; Sporulation response regulatory protein Spo0B; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:RKJ61628.1};
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000313|EMBL:RKJ61628.1};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000279120};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 40..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 351..461
FT /note="Sensor histidine kinase NatK C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14501"
SQ SEQUENCE 467 AA; 52958 MW; 560BBDFBA60FD251 CRC64;
MSEMGFMLFQ HIASGGETVL CAFCMAVFFR PYTAGRKNRM QKNIAVFLAY GMVYLMGEAF
SVSGWLCMVI VILLLMAGGR WLCMERKQVF LYGILFFCTR DMGRLITESL YYLFNGKIVQ
GLDNENMIYR NVAAGYSAFM VLRIILLLAM LLFLSKKLEK GPPELHTKEL CYLCLTPVVG
ILFENIIFRL LFTVKENVVF SLYGQYPAFI GLVPLIAVLF YAGMVVTVAS WQEMVGLQEE
KKKYFVEQQQ LAAIRERIGE VEQFYDGIRR MKHEMKNHLT NIKGLAGSGS YEEMEQYIAR
MDESMDAFEM SVRTGNAVTD VIVNDKQKAA ERMGIRFRSD FVYPASDRYN AYDIAIIVNN
LLQNALEACG RMTSGERYIS LSGSRKNRFF LISVKNSFEG EVVFDKSTNL PVSTKAPDVP
GGPAPLHGIG LSNVRREAAK YLGNVDIKVR KNEFSVTVLL QERSNHE
//
