ID A0A3A9JXA1_9THEO Unreviewed; 459 AA.
AC A0A3A9JXA1;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE SubName: Full=Radical SAM protein {ECO:0000313|EMBL:RKL62902.1};
GN ORFNames=DXT63_08960 {ECO:0000313|EMBL:RKL62902.1};
OS Thermoanaerobacteraceae bacterium SP2.
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae.
OX NCBI_TaxID=2292448 {ECO:0000313|EMBL:RKL62902.1, ECO:0000313|Proteomes:UP000271566};
RN [1] {ECO:0000313|Proteomes:UP000271566}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SP2 {ECO:0000313|Proteomes:UP000271566};
RA Grouzdev D.S., Krutkina M.S., Patutina E.O.;
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKL62902.1}.
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DR EMBL; QSNL01000014; RKL62902.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3A9JXA1; -.
DR OrthoDB; 9782387at2; -.
DR Proteomes; UP000271566; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd21128; SPASM_rSAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR007197; rSAM.
DR PANTHER; PTHR43524; RADICAL SAM SUPERFAMILY PROTEIN; 1.
DR PANTHER; PTHR43524:SF1; RADICAL SAM SUPERFAMILY PROTEIN; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR SFLD; SFLDG01386; main_SPASM_domain-containing; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000271566};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 113..328
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 459 AA; 52334 MW; ABC60C3094357586 CRC64;
MIVTQKWQPN LDFAKRYISE KVLQQLLSYL SRDPVRHMEQ ILSLGKILAR REEHRRNIEA
IEKAIATNPA INQLAEGLLK DTHSNVLHRL LYNWFINSAL LGIPRQRQLS DTLGFNVPHF
ILVDPTGACN LRCEGCWAGA YAKHDELSFE RLDRLFNEAK DLGIYWIVMS GGEPFLYPHL
FDLAAKHSDM AFMIYTNGTM IDDRVADKIV EVGNISPAFS LEGWENRTDQ RRGKGVFKKV
TEAMDRLRER GAVFGISLTA TRDNVDEITS DNFIDFLTEK GARYGWIFHY IPIGRNPNPE
LMLTPEQRAY MAERIPYIRS HKPILLGDFW NDGELTQGCI AGGRRYFHIT ASGAVEPCAF
VHFSTQNIND CSLKQVLQSP LFTTFQKRQP FCDDHLRPCP IIDVPEGLRQ IVKESGAKPT
HDGAEDVLKG EVGEFLDLRS TAWAKEVAKI RSEVRKNIC
//
