ID A0A3A9USC9_9FLAO Unreviewed; 319 AA.
AC A0A3A9USC9;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE RecName: Full=Arginase {ECO:0000256|ARBA:ARBA00018123};
DE EC=3.5.3.1 {ECO:0000256|ARBA:ARBA00012168};
GN ORFNames=D1817_04955 {ECO:0000313|EMBL:AXT19241.1};
OS Flavobacteriaceae bacterium.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae.
OX NCBI_TaxID=1871037 {ECO:0000313|EMBL:AXT19241.1, ECO:0000313|Proteomes:UP000260281};
RN [1] {ECO:0000313|EMBL:AXT19241.1, ECO:0000313|Proteomes:UP000260281}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AU392 {ECO:0000313|EMBL:AXT19241.1,
RC ECO:0000313|Proteomes:UP000260281};
RA Song W., Thomas T., Edwards R.;
RT "Complete genome sequences of pooled genomic DNA from 10 marine bacteria
RT using PacBio sequencing.";
RL Submitted (AUG-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + L-arginine = L-ornithine + urea; Xref=Rhea:RHEA:20569,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:16199, ChEBI:CHEBI:32682,
CC ChEBI:CHEBI:46911; EC=3.5.3.1;
CC Evidence={ECO:0000256|ARBA:ARBA00000227};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- PATHWAY: Nitrogen metabolism; urea cycle; L-ornithine and urea from L-
CC arginine: step 1/1. {ECO:0000256|ARBA:ARBA00005098}.
CC -!- SIMILARITY: Belongs to the arginase family. {ECO:0000256|PROSITE-
CC ProRule:PRU00742}.
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DR EMBL; CP031964; AXT19241.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3A9USC9; -.
DR OrthoDB; 9788689at2; -.
DR Proteomes; UP000260281; Chromosome.
DR GO; GO:0004053; F:arginase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0006525; P:arginine metabolic process; IEA:UniProtKB-KW.
DR CDD; cd09989; Arginase; 1.
DR Gene3D; 3.40.800.10; Ureohydrolase domain; 1.
DR InterPro; IPR014033; Arginase.
DR InterPro; IPR006035; Ureohydrolase.
DR InterPro; IPR023696; Ureohydrolase_dom_sf.
DR PANTHER; PTHR43782; ARGINASE; 1.
DR PANTHER; PTHR43782:SF3; ARGINASE; 1.
DR Pfam; PF00491; Arginase; 1.
DR PRINTS; PR00116; ARGINASE.
DR SUPFAM; SSF52768; Arginase/deacetylase; 1.
DR PROSITE; PS51409; ARGINASE_2; 1.
PE 3: Inferred from homology;
KW Arginine metabolism {ECO:0000256|ARBA:ARBA00022503};
KW Reference proteome {ECO:0000313|Proteomes:UP000260281}.
SQ SEQUENCE 319 AA; 35394 MW; 0E7F5D2C8FD402FF CRC64;
MKEIKIIKNR SDIGAGTRGS DMGIDAIEIA AININNNYFS RFNFEDVETE NESIYNKVNN
SFAKRIEHVF NQCLRVSNVV ERNLNEGVFP LVISGDHSSA LGTLSGIKAA NPDKRIGAVW
IDAHADLHSP YTSPSGNIHG MPLAAALGDD NLSCQINEVT GDTNTYWEAI KNIGIDGPKI
HSDDLVFFGV RDTEAPEDKQ IEKLNIKNYR VDEVRYRGLE VAVNEAIDKL KDCDMIYISF
DVDSMDCDLI SYGTGTPVAK GFDQYEAMQI INKLIETKKV TCLEFVEVNP LLDTKGNKMA
ETAFEVLDNV TSTLQETLN
//
