ID A0A3A9ZKY2_9ACTN Unreviewed; 760 AA.
AC A0A3A9ZKY2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=Helix-turn-helix domain-containing protein {ECO:0000313|EMBL:RKN47916.1};
GN ORFNames=D7223_12420 {ECO:0000313|EMBL:RKN47916.1};
OS Micromonospora endolithica.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=230091 {ECO:0000313|EMBL:RKN47916.1, ECO:0000313|Proteomes:UP000281726};
RN [1] {ECO:0000313|EMBL:RKN47916.1, ECO:0000313|Proteomes:UP000281726}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 12677 {ECO:0000313|EMBL:RKN47916.1,
RC ECO:0000313|Proteomes:UP000281726};
RX PubMed=15046305; DOI=10.1078/072320204322881781;
RA Hirsch P., Mevs U., Kroppenstedt R.M., Schumann P., Stackebrandt E.;
RT "Cryptoendolithic actinomycetes from antarctic sandstone rock samples:
RT Micromonospora endolithica sp. nov. and two isolates related to
RT Micromonospora coerulea Jensen 1932.";
RL Syst. Appl. Microbiol. 27:166-174(2004).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RKN47916.1}.
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DR EMBL; RBAK01000004; RKN47916.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3A9ZKY2; -.
DR OrthoDB; 7628974at2; -.
DR Proteomes; UP000281726; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR CDD; cd00093; HTH_XRE; 1.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR001387; Cro/C1-type_HTH.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF13560; HTH_31; 1.
DR Pfam; PF13181; TPR_8; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00530; HTH_XRE; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50943; HTH_CROC1; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000281726}.
FT DOMAIN 9..58
FT /note="HTH cro/C1-type"
FT /evidence="ECO:0000259|PROSITE:PS50943"
FT REGION 730..760
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 760 AA; 81542 MW; 012B13E24AE70256 CRC64;
METSFGDRLR ALRRRAGLTL EALAEASGVS ARAISDMERG RSRGPQDRTL VALFDGLGLG
GAERADLAAA ARAARAQNAS GRPRSGEPPR GVSDFVGREA ESKLIAQHAD GAGTGRMAPV
VLIHGQGGLG KTALALHAGE ELRARFPDGR CYLDLRGMDP TPLAVGAALR RLLQALGADP
GRIATSEDEQ ASQLRAILAE RRVLLLLDNA ADETQVRPLL PGTGTAMTIV TSRRTLAGLE
GVLRIGLAPL ADAEAAGLLR TIGGATSRSA SDTEIGTVAR LCGNLPLALR IAGTRFASRP
GWTMRHLIDR LADEERRLAN LTAGDTGVAA AFALSYAQLT GPTATLFRRL ALIPGDDFTA
PLAAVLVDTD HHHAEHLLDD LADLGLLQAV GDRYRLHDLI RLYAAECLRT DETRPERDAA
RRRMLDALID TAITAGRWYE PGHGAPPGHW RGLDPLDTQD RARAWLRAEL SNWVGALRAA
ARDGQHQQVV DIAESMHWYS DQSAKDGPWH EVYQRSRTAA AHLPDRRQEI THINYLAWVL
IYLELRYADG VELAMQAHRM ADEHGDAKGE AEALWLAGAG WARAGDHDRS LTAIRRAIDV
ADAAGIHDAC VQYLVSLGTA YKLAGRTDEA VDQYRAAIQQ AQVRPMSRTP RLVALSTGHN
GLLRTLTQAR RWPEALAEAP ATLTAVQRSG SVLQLSTTHL LIGLTYAGLG MRDAARAALT
RALELNGSMV QPDPETTEAA ESALAALDVP DDNGPAPPTL
//
