ID   A0A3B0J752_DROGU        Unreviewed;      1080 AA.
AC   A0A3B0J752;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Blast:Mesoderm induction early response protein 1 {ECO:0000313|EMBL:SPP75702.1};
GN   ORFNames=DGUA_6G003560 {ECO:0000313|EMBL:SPP75702.1};
OS   Drosophila guanche (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7266 {ECO:0000313|EMBL:SPP75702.1, ECO:0000313|Proteomes:UP000268350};
RN   [1] {ECO:0000313|Proteomes:UP000268350}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Alioto T., Alioto T.;
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00371}.
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DR   EMBL; OUUW01000001; SPP75702.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3B0J752; -.
DR   STRING; 7266.A0A3B0J752; -.
DR   Proteomes; UP000268350; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   CDD; cd11661; SANT_MTA3_like; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   InterPro; IPR004210; BESS_motif.
DR   InterPro; IPR000949; ELM2_dom.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR006578; MADF-dom.
DR   InterPro; IPR040138; MIER/MTA.
DR   InterPro; IPR001005; SANT/Myb.
DR   InterPro; IPR017884; SANT_dom.
DR   PANTHER; PTHR10865:SF28; ELM2 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR10865; METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN; 1.
DR   Pfam; PF02944; BESS; 1.
DR   Pfam; PF01448; ELM2; 1.
DR   Pfam; PF10545; MADF_DNA_bdg; 1.
DR   SMART; SM01189; ELM2; 1.
DR   SMART; SM00595; MADF; 1.
DR   SMART; SM00717; SANT; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS51031; BESS; 1.
DR   PROSITE; PS51156; ELM2; 1.
DR   PROSITE; PS51029; MADF; 1.
DR   PROSITE; PS51293; SANT; 1.
PE   4: Predicted;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00371}.
FT   DOMAIN          283..411
FT                   /note="ELM2"
FT                   /evidence="ECO:0000259|PROSITE:PS51156"
FT   DOMAIN          416..468
FT                   /note="SANT"
FT                   /evidence="ECO:0000259|PROSITE:PS51293"
FT   DOMAIN          763..842
FT                   /note="MADF"
FT                   /evidence="ECO:0000259|PROSITE:PS51029"
FT   DOMAIN          1040..1079
FT                   /note="BESS"
FT                   /evidence="ECO:0000259|PROSITE:PS51031"
FT   REGION          1..76
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          115..168
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          180..247
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          495..577
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          847..868
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          908..1021
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        10..25
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        51..75
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        190..211
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        495..519
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        928..942
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        980..1019
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1080 AA;  120230 MW;  1E83E1FE9898BD1D CRC64;
     MECGKSTEHS SRSASEASAD SGSLLNSDLV MPGRELTLTP TKRERRKSPA TSSDNTSTSV
     QAPMSPTSSL ADTTFEPTID MMVNDFDDEA TLNEEEALAN LEALNPDDEI ATLREESEMP
     IEELLAKYSM APSPAASSSK RSSGSRRRRA TKRQYQELDT ETAHASTSCA VAAQQEKVND
     FLDQCQDPGV GPSKENTSPS SQRNKSPMET DEPQAILSPD VTKKPHRSHL LDLYPDESFG
     ESPPIIGPLE ELESFTPLQA LFEEVEVDDD DEDSDNESDD ARKIIMVGTD YQADIPEGLS
     QYGDILPYEN EDLLIWEPSQ VSEREVEEYL AKIQETRALP PLEEGAEALA SDEQPSALPA
     PLVPQRVQQA PNAASDGETL AVVKDNEQAL HLLVQCGYDF NEALRRKRLN VLPLSDTMSS
     WSEEECLKFE EGIHKYGKDF YQIRQNQVRT RTMRELVHFY YLWKKSERRD QSFALNDTID
     HMDVFLNEAG TTSGIGNGNG NGNGNRNGSC SPHSSNGHSN GEHALDKDTT CSSRKPSSKS
     YSIMTGGIPQ PAGGAAGTIS KRTTPAPMTL EDREDKEEEA YQGPLVSICT GGGVQCVLEE
     VIGFGRVGVD GAEHIGFATA SHQCIRQRKL TTVKRSEPLR AAIPAEALHP DNIADASLRQ
     SLLLCARSAC ALFSVFFGLA FAIASASPES QKARHVNWLD RTRIFQFSVL FLRLSCVRRY
     STRRRSMEAA YNNASSSSAS PPAFSSSFAF TNTAKLPIET VKRLIAAVSR RPMLWLRNNV
     SGQKRSDITP IWFEVGQDVN LPGEKEREDN FRKVYIRNNL SNETPSTWRF YNDMRFMEHA
     VHENIMRQTR SSSKKHPPGH WTENNNIMDE KYDGPAVATE PICELSDSYD SELHQPSFSD
     ISSFFEDRDC LPAQPPESKR IKLEPSPAEE EDDDDFDEDA ASENEEERTK RSEAVNTPDP
     SLFTIEVLDD DEEELEVSSS NVKCKTNDTS INSQRSEPDV KPSLSQSQSQ SQSPTSDLPF
     KYISMDAATN TESSLAELQD DADRMFLLSL MPFLQKLDER RKLRVRQKLQ NVLIEELEFG
//