ID   A0A3B0JNC5_DROGU        Unreviewed;       571 AA.
AC   A0A3B0JNC5;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Blast:Pickpocket protein 28 {ECO:0000313|EMBL:SPP75059.1};
GN   ORFNames=DGUA_6G002787 {ECO:0000313|EMBL:SPP75059.1};
OS   Drosophila guanche (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7266 {ECO:0000313|EMBL:SPP75059.1, ECO:0000313|Proteomes:UP000268350};
RN   [1] {ECO:0000313|Proteomes:UP000268350}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Alioto T., Alioto T.;
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC       1.A.6) family. {ECO:0000256|ARBA:ARBA00007193,
CC       ECO:0000256|RuleBase:RU000679}.
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DR   EMBL; OUUW01000001; SPP75059.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3B0JNC5; -.
DR   OMA; CENECLA; -.
DR   Proteomes; UP000268350; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.287.820; Acid-sensing ion channel domain; 1.
DR   Gene3D; 1.10.287.770; YojJ-like; 1.
DR   InterPro; IPR001873; ENaC.
DR   PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR   PANTHER; PTHR11690:SF243; PICKPOCKET 12-RELATED; 1.
DR   Pfam; PF00858; ASC; 1.
DR   PRINTS; PR01078; AMINACHANNEL.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU000679};
KW   Ion transport {ECO:0000256|RuleBase:RU000679};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW   ECO:0000256|RuleBase:RU000679};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000679}.
FT   TRANSMEM        479..500
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   571 AA;  64296 MW;  FC4D27AB76080898 CRC64;
     MESSGAPQRQ GSSMFLLRSL GRSLKEFLKS TGLHGLKFVG DSSLSSWERS FFFCSFVVAL
     VVTCNLISNI YAKWDSTPVI IGISPQATSI LKVPFPAITI CNMNQVQSSQ VSHYREGSDE
     SAILKLLCNS EMEDSEDLDD DVSRSNFAQS TLSLSDFVSN HSQRCDKMLL YCRFNAVEHN
     CSHLFQQLMT DEGLCCVFNF QPPEFLYKPF SNSRRNLTMK NGFEAVKWNP ETGYPDKLPT
     KYYPATAIGT GIALGFTAVL DAQMSEYYCS STNGPGFKVY FHNPTEVPVV KEAGLITAIG
     FETNYRMEVL RAEAVPAIRS ISRDGRQCLF GNEKDLIFYQ TYTRLNCEHE CMAGYLYESC
     ACIPFVYPQI YSNATTCGMR DTLCLHRAQQ AAIRPGWVKC RQQCLPGCFD LSYMASGFSF
     PLATSKFQLA NPLVESINKS YLSGNIAVIN VYYRESVYYG NTKNAYVGLT EFLSNIGGVM
     GLFMGFSVIS LAEIFYFLLL KPLVELFLWK RSAQVDAQNS IKHNAFAMEQ PEMIDNKAIV
     WHTRELYPQG PKLKLSRTVK RNRNKTNVFA Q
//