ID   A0A3B0JPR5_DROGU        Unreviewed;       538 AA.
AC   A0A3B0JPR5;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=glycerol kinase {ECO:0000256|ARBA:ARBA00012099};
DE            EC=2.7.1.30 {ECO:0000256|ARBA:ARBA00012099};
DE   AltName: Full=ATP:glycerol 3-phosphotransferase {ECO:0000256|ARBA:ARBA00043149};
GN   ORFNames=DGUA_6G003480 {ECO:0000313|EMBL:SPP75639.1};
OS   Drosophila guanche (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7266 {ECO:0000313|EMBL:SPP75639.1, ECO:0000313|Proteomes:UP000268350};
RN   [1] {ECO:0000313|Proteomes:UP000268350}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Alioto T., Alioto T.;
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol kinase
CC       pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC       {ECO:0000256|ARBA:ARBA00005190}.
CC   -!- SIMILARITY: Belongs to the FGGY kinase family.
CC       {ECO:0000256|ARBA:ARBA00009156, ECO:0000256|RuleBase:RU003733}.
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DR   EMBL; OUUW01000001; SPP75639.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3B0JPR5; -.
DR   UniPathway; UPA00618; UER00672.
DR   Proteomes; UP000268350; Unassembled WGS sequence.
DR   GO; GO:0004370; F:glycerol kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd07769; FGGY_GK; 1.
DR   Gene3D; 3.30.420.40; -; 2.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR000577; Carb_kinase_FGGY.
DR   InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR   InterPro; IPR018485; FGGY_C.
DR   InterPro; IPR018484; FGGY_N.
DR   PANTHER; PTHR10196:SF69; GLYCEROL KINASE; 1.
DR   PANTHER; PTHR10196; SUGAR KINASE; 1.
DR   Pfam; PF02782; FGGY_C; 1.
DR   Pfam; PF00370; FGGY_N; 1.
DR   PIRSF; PIRSF000538; GlpK; 1.
DR   SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR   PROSITE; PS00445; FGGY_KINASES_2; 1.
PE   3: Inferred from homology;
KW   Kinase {ECO:0000256|RuleBase:RU003733, ECO:0000313|EMBL:SPP75639.1};
KW   Transferase {ECO:0000256|RuleBase:RU003733}.
FT   DOMAIN          20..266
FT                   /note="Carbohydrate kinase FGGY N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00370"
FT   DOMAIN          276..497
FT                   /note="Carbohydrate kinase FGGY C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02782"
SQ   SEQUENCE   538 AA;  59429 MW;  4EB353ADE4A60EB4 CRC64;
     MNNGRYGRFG ALIGIAYVSG THCKFLIYST KNAEVLAYHE LKLRQIVHQA GWLEYDPSEI
     WKYMQECIET AYKNLVILEI DPHDIIAVGI VNQRGTTVLW NKQTGQPLYN AIGWSDSRST
     SVLRRILQNV KQNVDYVRHR TGLPLSGCFS AFKIRWLMES VPAVADSIKE DKCLFGTLDS
     WLLWNLTGGV QAGVHSTDIT NAHYTSLMNL SSQQWDAKLC QFFKLPINIL PRIRSNSEIF
     GYVLDGPLLG VPIAGVMGEQ SACLLGQLCI KAGQNVCTLD DSCFVLLNTG TEKLESDNGL
     ITGVAHQLGP RAATNYSLEG AISNAGSTVT WLREKLRINT EINSNDNVVE SLNTFIGDSS
     MISSSCSSSM LNTECGLAAK RSEITLVPAF HGLYAPYWRY DARGIILGLS SQTTAENITQ
     AAYEATGFQI YEVLEAFKRD TPNWDHASTH PVLTFGGEYA EDTHLVQFIA DIMGYMLERP
     QTASPAGLGV MIAAGVTMGV VSLEYATKMY APPTDVFSPT TTPNRKCRGR LYLRQHSK
//