ID   A0A3B0JSH9_DROGU        Unreviewed;       517 AA.
AC   A0A3B0JSH9;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Blast:Bifunctional coenzyme A synthase {ECO:0000313|EMBL:SPP85074.1};
GN   ORFNames=DGUA_6G014958 {ECO:0000313|EMBL:SPP85074.1};
OS   Drosophila guanche (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7266 {ECO:0000313|EMBL:SPP85074.1, ECO:0000313|Proteomes:UP000268350};
RN   [1] {ECO:0000313|Proteomes:UP000268350}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Alioto T., Alioto T.;
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; OUUW01000009; SPP85074.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3B0JSH9; -.
DR   STRING; 7266.A0A3B0JSH9; -.
DR   OMA; TQCLQSY; -.
DR   OrthoDB; 460288at2759; -.
DR   Proteomes; UP000268350; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004140; F:dephospho-CoA kinase activity; IEA:InterPro.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:InterPro.
DR   CDD; cd02022; DPCK; 1.
DR   CDD; cd02164; PPAT_CoAS; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   HAMAP; MF_00376; Dephospho_CoA_kinase; 1.
DR   InterPro; IPR004821; Cyt_trans-like.
DR   InterPro; IPR001977; Depp_CoAkinase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   NCBIfam; TIGR00125; cyt_tran_rel; 1.
DR   NCBIfam; TIGR00152; dephospho-CoA kinase; 1.
DR   PANTHER; PTHR10695:SF64; BIFUNCTIONAL COENZYME A SYNTHASE; 1.
DR   PANTHER; PTHR10695; DEPHOSPHO-COA KINASE-RELATED; 1.
DR   Pfam; PF01121; CoaE; 1.
DR   Pfam; PF01467; CTP_transf_like; 1.
DR   SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51219; DPCK; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          146..287
FT                   /note="Cytidyltransferase-like"
FT                   /evidence="ECO:0000259|Pfam:PF01467"
SQ   SEQUENCE   517 AA;  57415 MW;  6B94C4F04551DB95 CRC64;
     MASTGLLVVS NIKHLGKSLR SIEKYVSSLY IHLNVAGSTS NSSAAAPPVW GRLISQLYAN
     SSSYVGNQID LRVLVSPLRP GVDGPLKLRK PVDMIFSDAH HPELCDRLRA ALNISQPTIF
     LEDSSSSDLS PQKDSTESHK MYPSVVLGGT FDRIHLGHKI FLTQAVLRTC KRLVVGVTTA
     AMTKSKTLPD LILPVEERIA QLREFLTDID STLQYEIVPI DDPFGPTQHD PDLDMIVVSA
     ETLRGGQKVN ELRSGKQLRE LDIFVIDIVE SNVHDGIHET KISSSNTRID LLGSRWRKPE
     PRPQLPARPY IIGLSGGIAS GKSKMAERLS KMGAHVIDCD KVAHDVYEPG QVCYKLIVQH
     FGKGILSADG RIDRTKLGPL VFGNPQELQA LNGIVWPQLI EEVNRRLEAL RAGTVVPKVV
     VLEAAVLLRA GWESNCHEVW SMIVPPEEAV KRVMKRNSLS EEEARKRLSS QMPNHEIVAK
     SHVIFSSQWD FDFTQKQADR TWKMLNSELD SHHSSSL
//