ID   A0A3B0JUT0_DROGU        Unreviewed;       412 AA.
AC   A0A3B0JUT0;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Blast:Endothelial lipase {ECO:0000313|EMBL:SPP74828.1};
GN   ORFNames=DGUA_6G002522 {ECO:0000313|EMBL:SPP74828.1};
OS   Drosophila guanche (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7266 {ECO:0000313|EMBL:SPP74828.1, ECO:0000313|Proteomes:UP000268350};
RN   [1] {ECO:0000313|Proteomes:UP000268350}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Alioto T., Alioto T.;
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC       {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|RuleBase:RU004262}.
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DR   EMBL; OUUW01000001; SPP74828.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3B0JUT0; -.
DR   STRING; 7266.A0A3B0JUT0; -.
DR   Proteomes; UP000268350; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0016298; F:lipase activity; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   CDD; cd00707; Pancreat_lipase_like; 1.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR013818; Lipase.
DR   InterPro; IPR033906; Lipase_N.
DR   InterPro; IPR000734; TAG_lipase.
DR   PANTHER; PTHR11610; LIPASE; 1.
DR   PANTHER; PTHR11610:SF169; LIPASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00151; Lipase; 1.
DR   PRINTS; PR00821; TAGLIPASE.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT   DOMAIN          62..340
FT                   /note="Lipase"
FT                   /evidence="ECO:0000259|Pfam:PF00151"
FT   REGION          368..412
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        368..386
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   412 AA;  45408 MW;  8CD8E470E943B90B CRC64;
     MCSHFCLRVR PFSIALSRGA PAPTAVASES ARTSNLCCTR GKPSARCLMH TESPESRGCC
     HFRRNRNTAQ LLHLNDDGRL AQSNFNFNYP LVVYLHGFSE SATGERQSSQ ELKDAFLRRG
     NHNVILIDWS AMTAVPWYSN SVENLPITAR YIARFLRYLV GRGHAAKHIH LIGFSLGAEV
     AGFAGKQLQE WGIKLTRITA LDPALPLFEG NSSNRRLSPS DARFVDVIHT DGGILGNPTA
     MGHADFYPNG GRPLQPGCAR QEIANNRWLG IIIGCSHQRA WEYFVESVAQ PRGFPAKRCE
     PSPTFGVCRD GGKGAAFMGM GADPRLRGKF YLETNGAKPF GRNSRTQAIV SLAPQLPIAY
     KLPTIAARPT VQSQSRSQTL VNQYGRPEQD SMREEDAEEE DENNSIDSSS LT
//