ID A0A3B0JYH0_DROGU Unreviewed; 351 AA.
AC A0A3B0JYH0;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Blast:Heparin sulfate O-sulfotransferase {ECO:0000313|EMBL:SPP85482.1};
GN ORFNames=DGUA_6G003938 {ECO:0000313|EMBL:SPP85482.1};
OS Drosophila guanche (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7266 {ECO:0000313|EMBL:SPP85482.1, ECO:0000313|Proteomes:UP000268350};
RN [1] {ECO:0000313|Proteomes:UP000268350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Alioto T., Alioto T.;
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004606}; Single-
CC pass type II membrane protein {ECO:0000256|ARBA:ARBA00004606}.
CC -!- SIMILARITY: Belongs to the sulfotransferase 3 family.
CC {ECO:0000256|ARBA:ARBA00010569}.
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DR EMBL; OUUW01000010; SPP85482.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B0JYH0; -.
DR STRING; 7266.A0A3B0JYH0; -.
DR OMA; NITANMH; -.
DR OrthoDB; 5401406at2759; -.
DR Proteomes; UP000268350; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008146; F:sulfotransferase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007734; Heparan_SO4_2-O-STrfase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005331; Sulfotransferase.
DR PANTHER; PTHR12129; HEPARAN SULFATE 2-O-SULFOTRANSFERASE; 1.
DR PANTHER; PTHR12129:SF17; HEPARAN SULFATE 2-O-SULFOTRANSFERASE 1; 1.
DR Pfam; PF03567; Sulfotransfer_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:SPP85482.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 351 AA; 41097 MW; 41FCA3E84F59F1A0 CRC64;
MLKMFILLRP THWLVLIALC ILTCAGYWLL WSEIRLENAF KPLTKGTEGG SALEQSLGVP
VATAVVDSFD YEEQLVVLYN RVPKTGSTSF VNIAYDLCKL NKYHVLHINV TANMHVLSLP
NQIAFVRNVS KWHEMKPALY HGHMAFLDFS KFQIAHKPIY INLVRKPLDR LVSYYYFLRF
GDNYRPNLVR KKAGNKITFD ECVIQKQADC DPKNMWLQIP FFCGHAAECW EPGSDWALDQ
AKRNLVNEYF LVGVTEQMYE FVDLLERSLP RIFHGFREHY QTSNKSHLRV TSSKLPPSES
TIKSIQKTKI WQMENDLYEF ALAQFEFNKK KLMQPDNKHL QKFMYEKIRP K
//
