ID   A0A3B0K4L9_DROGU        Unreviewed;       795 AA.
AC   A0A3B0K4L9;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   28-JUN-2023, entry version 14.
DE   SubName: Full=Blast:Actin-binding LIM protein 3 {ECO:0000313|EMBL:SPP88243.1};
GN   ORFNames=DGUA_6G016079 {ECO:0000313|EMBL:SPP88243.1};
OS   Drosophila guanche (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7266 {ECO:0000313|EMBL:SPP88243.1, ECO:0000313|Proteomes:UP000268350};
RN   [1] {ECO:0000313|Proteomes:UP000268350}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Alioto T., Alioto T.;
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; OUUW01000013; SPP88243.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3B0K4L9; -.
DR   Proteomes; UP000268350; Unassembled WGS sequence.
DR   GO; GO:0003779; F:actin binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0007010; P:cytoskeleton organization; IEA:InterPro.
DR   CDD; cd09327; LIM1_abLIM; 1.
DR   CDD; cd09328; LIM2_abLIM; 1.
DR   CDD; cd09329; LIM3_abLIM; 1.
DR   CDD; cd09330; LIM4_abLIM; 1.
DR   Gene3D; 2.10.110.10; Cysteine Rich Protein; 4.
DR   Gene3D; 1.10.950.10; Villin headpiece domain; 1.
DR   InterPro; IPR003128; Villin_headpiece.
DR   InterPro; IPR036886; Villin_headpiece_dom_sf.
DR   InterPro; IPR001781; Znf_LIM.
DR   PANTHER; PTHR24213; ACTIN-BINDING LIM PROTEIN; 1.
DR   PANTHER; PTHR24213:SF9; UNCOORDINATED 115A, ISOFORM B-RELATED; 1.
DR   Pfam; PF00412; LIM; 4.
DR   Pfam; PF02209; VHP; 1.
DR   SMART; SM00132; LIM; 4.
DR   SMART; SM00153; VHP; 1.
DR   SUPFAM; SSF57716; Glucocorticoid receptor-like (DNA-binding domain); 5.
DR   SUPFAM; SSF47050; VHP, Villin headpiece domain; 1.
DR   PROSITE; PS51089; HP; 1.
DR   PROSITE; PS00478; LIM_DOMAIN_1; 4.
DR   PROSITE; PS50023; LIM_DOMAIN_2; 3.
PE   4: Predicted;
KW   LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW   ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT   DOMAIN          6..65
FT                   /note="LIM zinc-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50023"
FT   DOMAIN          66..125
FT                   /note="LIM zinc-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50023"
FT   DOMAIN          179..238
FT                   /note="LIM zinc-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS50023"
FT   DOMAIN          730..795
FT                   /note="HP"
FT                   /evidence="ECO:0000259|PROSITE:PS51089"
FT   REGION          127..157
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          385..526
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          553..574
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        134..157
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        394..416
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        480..506
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   795 AA;  88053 MW;  4ADF9ACE8EFF8F84 CRC64;
     MGKQKIYCAK CTKKCSGEVL RVADNHFHKA CFQCCQCKKS LATGGFFTKD SAYYCIPDYQ
     RLYGTKCATC QQYVEGEVVS TMGKTYHQKC FTCSKCQQPF KSGSKVTNTG KEVLCEHCVS
     GGGGGGGVGG GAPVSPSRQT SVSSPAPPAE SPTRATAHQQ LTGGVISHKA HLKEDYDPND
     CAGCGELLKE GQALVALDRQ WHVSCFRCKA CQVVLNGEYM GKDAVPYCEK CYQKGFGVKC
     AYCNRFISGK VLQAGDNHHF HPTCARCTKC GDPFGDGEEM YLQGSAIWHP RCGPGPSESG
     IILNGGGGNT SVVGGASNGN FTDTECDRMS SSALSEMHYR TVSPGLILRE YGRPIGEDIS
     RIYTYSYLTD APHYLRKPIE PYDKTPLSPH FHRPASYATT SNAGSVAGSR PPSRPHSRTR
     SAMKVLVDAI RSETPRPKSP GMNNEEPIEL SHYPDAKKPL PGEQPKIERD DFPAPPYPYT
     DPERRRRYSD TYKGVPVSDD EDENVQNGKQ TNGNAKNGEE QRRLQREAEQ LEKLNSGIGS
     VIAKDLKEHA KYRKWKQNNL DPRNASRTPS ASKEPIYKLR YESPIGASPS RHLDAQKPFY
     EDEMFDRSTS YRGSLGKSLG NAPSYNAIHS YRSPPKPGYG FKTTTLPYIR NGYSSDFSYG
     GLGDKTHSTD LSCGKSEASV DSITEGDRRA LMGGDLPASS TYSGALSYHY PQAGLIRRSL
     PNMAHSMLVH EPAKIYPYHL LLITNYRLPS DVDRCNLERH LSDIEFEHIL QCARSEFYRL
     PQWRRNELKR RVKLF
//