ID A0A3B0K7U4_DROGU Unreviewed; 434 AA.
AC A0A3B0K7U4;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Blast:Thiamine transporter 1 {ECO:0000313|EMBL:SPP82099.1};
GN ORFNames=DGUA_6G013911 {ECO:0000313|EMBL:SPP82099.1};
OS Drosophila guanche (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7266 {ECO:0000313|EMBL:SPP82099.1, ECO:0000313|Proteomes:UP000268350};
RN [1] {ECO:0000313|Proteomes:UP000268350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Alioto T., Alioto T.;
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|PIRNR:PIRNR028739}; Multi-
CC pass membrane protein {ECO:0000256|PIRNR:PIRNR028739}.
CC -!- SIMILARITY: Belongs to the reduced folate carrier (RFC) transporter (TC
CC 2.A.48) family. {ECO:0000256|ARBA:ARBA00005773,
CC ECO:0000256|PIRNR:PIRNR028739}.
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DR EMBL; OUUW01000006; SPP82099.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B0K7U4; -.
DR OMA; YVANRIF; -.
DR OrthoDB; 51626at2759; -.
DR Proteomes; UP000268350; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0090482; F:vitamin transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR002666; Folate_carrier.
DR InterPro; IPR036259; MFS_trans_sf.
DR NCBIfam; TIGR00806; rfc; 1.
DR PANTHER; PTHR10686; FOLATE TRANSPORTER; 1.
DR PANTHER; PTHR10686:SF18; FOLATE-LIKE TRANSPORTER 3; 1.
DR Pfam; PF01770; Folate_carrier; 1.
DR PIRSF; PIRSF028739; Folate_carrier; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|PIRNR:PIRNR028739, ECO:0000256|SAM:Phobius};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|PIRNR:PIRNR028739}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..434
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017248510"
FT TRANSMEM 46..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 327..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 434 AA; 47621 MW; 0A35FDFA2DC06855 CRC64;
MKYWLKISLL LCTFGFLREL RPSEPYVTEY LAGDYGNLTT EQVYQNVYPF GTYSVLAQLV
IVFLITDLVR YKPVIVLSAV AGIVLFAMQI WCDTLGMLQV AQLFYGFFTA AEVAYYTYIY
AKVDKERYQI VTGHTRAAIL SGKFLGGLVA QVLVSTDTMN YGELYYISLT TQIISLGVSL
VLPSVPRSLY FYATDASPSS SPTPAGEEIA PQFSMKNATR LLCYHLVSSY SNPIVLQWSV
WWSLATCGQI QVISYIQFLW KEVAPQHQSS YNGGVEAVAT LLGAVGAIAA GMLNSNKRRS
CYMLCNSICA AVLGALLLYA SQTKVIWVAY VNYVIFCAIF FFIITVAGAI VAENLVEDSF
GLVFGINTLV GLLLQTILTI VVVEPGTGFG LGLRDQYLVN GGYFVCLGAI YGLGIIIAKL
CARSSNSKQV QITT
//
