ID A0A3B0K9S5_DROGU Unreviewed; 663 AA.
AC A0A3B0K9S5;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=Anoctamin {ECO:0000256|RuleBase:RU280814};
GN ORFNames=DGUA_6G019583 {ECO:0000313|EMBL:SPP89452.1};
OS Drosophila guanche (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7266 {ECO:0000313|EMBL:SPP89452.1, ECO:0000313|Proteomes:UP000268350};
RN [1] {ECO:0000313|Proteomes:UP000268350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Alioto T., Alioto T.;
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU280814}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU280814}.
CC -!- SIMILARITY: Belongs to the anoctamin family.
CC {ECO:0000256|ARBA:ARBA00009671, ECO:0000256|RuleBase:RU280814}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU280814}.
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DR EMBL; OUUW01000021; SPP89452.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B0K9S5; -.
DR Proteomes; UP000268350; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007632; Anoctamin.
DR InterPro; IPR049452; Anoctamin_TM.
DR PANTHER; PTHR12308; ANOCTAMIN; 1.
DR PANTHER; PTHR12308:SF74; ANOCTAMIN; 1.
DR Pfam; PF04547; Anoctamin; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU280814};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU280814};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU280814}.
FT TRANSMEM 227..250
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT TRANSMEM 256..276
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT TRANSMEM 323..346
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT TRANSMEM 366..386
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT TRANSMEM 413..432
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT TRANSMEM 444..466
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT TRANSMEM 565..589
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU280814"
FT DOMAIN 219..637
FT /note="Anoctamin transmembrane"
FT /evidence="ECO:0000259|Pfam:PF04547"
FT REGION 37..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 663 AA; 77189 MW; 5B9A9DC41219B317 CRC64;
MMSEDAKSPG PRTRNIIENQ LFRRQRSLKL EALQRQRTLQ GDDDTDVAEP FDKVSQQGNE
SEARKTLSLS RLQTQIVIIF TEKAKLRHCQ DVEKIIQEFG IQTTLEIVGN TEKYLYLSAS
LDTLLRLADV AELEKKTTTG SMQKFNNGCI SDFLLPGMGK DQILRYCEIP VLIKDVIKPS
IKSYIQKGYI EDMFPLHDIL YLDRFKWNLK RTRLPIEDIR NYFGSSIGLY FGFIEFYTKA
LIFPAVFGIL QYLFDLNLSI VCSFYVVWTT IFLELWKRKC AGYSYRWGTI EMSSLDKPRS
AYQGQLKPDP ITGKMTLHYP MRYTYLQMYC ISYPVVLVCV VAAGWFALYQ FQIEAEVLAD
FGADSWLLYV PVIVQSILIA IFSWAYEKLA TFLTKLENHR TRSQYDRHRV NKLMLFEIVN
NFFSQFYIAF VLQDLKQLKY QLMMQLLIFQ LLCIAQEIGI PLMAVLRQKY VKFRHREVAP
EKLDNISDQP RYEQSFYESG LDAYHSTYED YLQVCIQFGF VVLFAAVAPF AAIGALVNNV
FAVHIDMFKL CNIFKRPFAR RAKNIGAWQL AFELLSVMSL LSNCGLLFLQ PNVKEFFSHW
LPSVPDLSFV IFEHLLLGLK FIIHKVIHER PRWVRIGLLK ADFETSQALK QLKKFKTEAN
KMA
//
