ID   A0A3B0KH52_DROGU        Unreviewed;       182 AA.
AC   A0A3B0KH52;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=Adenosine 5'-monophosphoramidase HINT3 {ECO:0000256|ARBA:ARBA00039802};
DE   AltName: Full=Histidine triad nucleotide-binding protein 3 {ECO:0000256|ARBA:ARBA00042361};
GN   ORFNames=DGUA_6G014950 {ECO:0000313|EMBL:SPP85066.1};
OS   Drosophila guanche (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7266 {ECO:0000313|EMBL:SPP85066.1, ECO:0000313|Proteomes:UP000268350};
RN   [1] {ECO:0000313|Proteomes:UP000268350}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Alioto T., Alioto T.;
RL   Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=adenosine 5'-phosphoramidate + H2O = AMP + NH4(+);
CC         Xref=Rhea:RHEA:67916, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938,
CC         ChEBI:CHEBI:57890, ChEBI:CHEBI:456215;
CC         Evidence={ECO:0000256|ARBA:ARBA00024472};
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DR   EMBL; OUUW01000009; SPP85066.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A3B0KH52; -.
DR   STRING; 7266.A0A3B0KH52; -.
DR   OMA; YHYLAIP; -.
DR   OrthoDB; 2782915at2759; -.
DR   Proteomes; UP000268350; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.
DR   CDD; cd01278; aprataxin_related; 1.
DR   Gene3D; 3.30.428.10; HIT-like; 1.
DR   InterPro; IPR011146; HIT-like.
DR   InterPro; IPR036265; HIT-like_sf.
DR   PANTHER; PTHR12486:SF5; ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT3; 1.
DR   PANTHER; PTHR12486; APRATAXIN-RELATED; 1.
DR   Pfam; PF11969; DcpS_C; 1.
DR   SUPFAM; SSF54197; HIT-like; 1.
DR   PROSITE; PS51084; HIT_2; 1.
PE   4: Predicted;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          48..161
FT                   /note="HIT"
FT                   /evidence="ECO:0000259|PROSITE:PS51084"
FT   MOTIF           141..145
FT                   /note="Histidine triad motif"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00464"
SQ   SEQUENCE   182 AA;  20282 MW;  61A808FC397A97CF CRC64;
     MLGESLSLFK RKKTIFAALA GLGLLGLVAV YNCGANNPTA AALQDKCLFC DFANGRQGPP
     PVLEVQTDEY VIFKDKSPAA TYHYLAIPKQ HFDSFSVLNR SHIGLVMQME SGMVELLKSK
     NVDPSKAIIG FHIPPFISVK HLHLHGIYPP SEMSLWNRIN FMSSFWFKTA KDANEALELR
     EL
//