ID A0A3B0KUQ7_DROGU Unreviewed; 1269 AA.
AC A0A3B0KUQ7;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Blast:Ankyrin-2 {ECO:0000313|EMBL:SPP89061.1};
GN ORFNames=DGUA_6G019289 {ECO:0000313|EMBL:SPP89061.1};
OS Drosophila guanche (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7266 {ECO:0000313|EMBL:SPP89061.1, ECO:0000313|Proteomes:UP000268350};
RN [1] {ECO:0000313|Proteomes:UP000268350}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Alioto T., Alioto T.;
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}. Membrane
CC {ECO:0000256|ARBA:ARBA00004370}.
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DR EMBL; OUUW01000017; SPP89061.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A3B0KUQ7; -.
DR Proteomes; UP000268350; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051179; P:localization; IEA:UniProt.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd08317; Death_ank; 1.
DR Gene3D; 2.60.220.30; -; 2.
DR Gene3D; 2.60.40.2660; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR040745; Ankyrin_UPA.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000488; Death_domain.
DR InterPro; IPR000906; ZU5_dom.
DR PANTHER; PTHR24123:SF33; ANKYRIN 2, ISOFORM U; 1.
DR PANTHER; PTHR24123; ANKYRIN REPEAT-CONTAINING; 1.
DR Pfam; PF12796; Ank_2; 3.
DR Pfam; PF13637; Ank_4; 1.
DR Pfam; PF13857; Ank_5; 1.
DR Pfam; PF00531; Death; 1.
DR Pfam; PF17809; UPA_2; 1.
DR Pfam; PF00791; ZU5; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 10.
DR SMART; SM00005; DEATH; 1.
DR SMART; SM00218; ZU5; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 10.
DR PROSITE; PS50088; ANK_REPEAT; 10.
DR PROSITE; PS50017; DEATH_DOMAIN; 1.
DR PROSITE; PS51145; ZU5; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 38..70
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 71..103
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 104..136
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 137..169
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 170..202
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 203..235
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 236..268
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 268..300
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 301..333
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 334..366
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT DOMAIN 511..667
FT /note="ZU5"
FT /evidence="ECO:0000259|PROSITE:PS51145"
FT DOMAIN 1042..1128
FT /note="Death"
FT /evidence="ECO:0000259|PROSITE:PS50017"
SQ SEQUENCE 1269 AA; 140171 MW; 0808E61C1C2F734D CRC64;
MHTSRYSQHT KIWLFSGCMN IVIYLLQHDA NPDIPTIRGE TPLHLASRAN QTDIIRILLR
NGAQVDAVAR EGQTPLHVAS RLGNIDIIML MLQHGANINA ETKDKYAALH IAAKEGQEEV
CLSLLESGAR LDGVTQKGFT PLHLASKYGK EKVVALLLEK GASIDCQGKN DVTPLHVAAH
YNHQPVVAVL LEKGASPQIC ARNGHSAVHI VAKKNNLEMA QQLVQHGADV RAISKSGFSP
LHLAAQEGHL PMVEFLLENG ATSAAARNGL TPLHLASQEG HVPVARTLLE NGAKISNRTK
NGYTPLHIAA HYGQINLVKY LLENDADIEM STNIGYTPLH QAAQQGHIMI INLLLRHKAN
PDALTNSGKT ALNIASNLGY VTAVETLKVV TQISITNTST GVVEEKYKVV SPELMHETLL
SDSEDEGGDE LLDHNQYKYM ATDDLKANYG HDHDHPNFDT TNPGNDQVDV SVRHPLEKEM
IDHEEQGLNA STTGRQCDNA LIVRPPVHLG FLVSFLVDAR GGSMRGYRHS GVRIIVPPKA
CSEPTRITCR YVKPQRVANP PPLMEGEALV SRILEMSPVE GKFLSPITLE VPHFGSLREN
EREIIILRSD NGESWREHSL YENEEQNLDS LNDTIDTDVN PLEELHTSRI VRIVTQNVPH
FFAVVSRVRQ EVHAIGPDGG TVFSMAVPQV QAIFPPHALT KKIRVGLQAQ PVDLVGCSKL
LGQGVAVSPV VTVEPRRRKF HKAITLSIPA PKACTKGMVN ASYGNGNANP PTLRLLCSIT
GGQTRAAWED VTGSTPLAFV KDSVTFTTTV SARFWLMDCR NIADAGRMAT ELYTYMAQVP
FVVKFVIFAK RITYTEAKFS VFCMTDDKED KTLEQQEYFI EVAKSRDIEV LQDQTIYIEF
SGNLVPVLKS GEQLNTKFQA FRENRLSFIV HIKDPELPHS RICFMSEPKV GPGEAPQNPI
CALNVSVHDE KLSAHNENGI VDGIVNGNIF YKEINRNDLI FTEMKACTAE TMEIDNPNKN
GITEQPKNQK LKADSTEGFH HAEKRLLDIS ILIGSDWPQL LKELGVPETD IDLFNAENLG
DLTSEQRMLM LQLRREEEQQ GLSAAEVLTQ ALNRIGRVDI IDKCISNMGH IIDESELPLN
TARKNVSLPP IPTYTGTDSP QMEDGNLCTT PPSTPIQDET NQSGCETRGI QKTVSKHTMQ
LLGKAPERVN HRKEALTDDS FMTGDYQYEN EPIDVTEIAK ELTVQSIMLQ KDATNVKMSG
NSAIDESKK
//
