ID   A0A3B1IC49_ASTMX        Unreviewed;       431 AA.
AC   A0A3B1IC49;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=Protein NDRG3 {ECO:0000256|ARBA:ARBA00015425};
OS   Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Characidae; Astyanax.
OX   NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000027457.1, ECO:0000313|Proteomes:UP000018467};
RN   [1] {ECO:0000313|Proteomes:UP000018467}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA   Jeffery W., Warren W., Wilson R.K.;
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000018467}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX   PubMed=25329095; DOI=10.1038/ncomms6307;
RA   McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA   Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA   Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA   Yoshizawa M., Warren W.C.;
RT   "The cavefish genome reveals candidate genes for eye loss.";
RL   Nat. Commun. 5:5307-5307(2014).
RN   [3] {ECO:0000313|Ensembl:ENSAMXP00000027457.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the NDRG family.
CC       {ECO:0000256|ARBA:ARBA00005598}.
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DR   AlphaFoldDB; A0A3B1IC49; -.
DR   Ensembl; ENSAMXT00000042887.1; ENSAMXP00000027457.1; ENSAMXG00000043104.1.
DR   GeneTree; ENSGT00950000182872; -.
DR   Proteomes; UP000018467; Unassembled WGS sequence.
DR   Bgee; ENSAMXG00000043104; Expressed in brain and 14 other cell types or tissues.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR004142; NDRG.
DR   PANTHER; PTHR11034; N-MYC DOWNSTREAM REGULATED; 1.
DR   PANTHER; PTHR11034:SF20; PROTEIN NDRG3; 1.
DR   Pfam; PF03096; Ndr; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018467}.
FT   REGION          29..52
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          382..431
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        382..415
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   431 AA;  47821 MW;  FD518585058FE34A CRC64;
     MNRFSELPRA VRHWLSAAVW LRLFPRRERE RERTEQNRTG AEGRSSTNSP GYTLLTHRSS
     RAFYSQTNGR NFQDFDCQEH DIETPHGVLH VTLRGTPKGN RPVILTYHDI GLNHKSCFNT
     LFNFEDMQEI TQHFAVVHVD APGQQENAPP FPSGYQYPTM DELAEMLPSV LTQLKINSVI
     GIGVGAGAYI LTRLALNQST LVEGLVLINV DPCAKGWMDW AASKLSGWTS NLVDIVMGHH
     FSTDELTENQ EIIQTYRLHI AQDINQDNLA LFCNSYNGRR DLEIERPILG INEETVNTLK
     CPALLVVGDT SPAVEAVVEC NSRLNPTKTT LLKMADCGGL PQVVQPGKLA EAFKYFVQGM
     GYIPHVLLSH LSSESVPTAS MTRLARSRTH SASSVSSVEG VRSRTHTSSQ AEGAVAGHDN
     QARPQTMEVS C
//