ID A0A3B1II40_ASTMX Unreviewed; 551 AA.
AC A0A3B1II40;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Kelch-like protein 32 {ECO:0000313|Ensembl:ENSAMXP00000029366.1};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000029366.1, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000029366.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B1II40; -.
DR STRING; 7994.ENSAMXP00000029366; -.
DR Ensembl; ENSAMXT00000039966.1; ENSAMXP00000029366.1; ENSAMXG00000040181.1.
DR GeneTree; ENSGT00940000165068; -.
DR InParanoid; A0A3B1II40; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000040181; Expressed in muscle tissue and 8 other cell types or tissues.
DR CDD; cd01165; BTB_POZ; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45972; BTB_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45972:SF2; KELCH-LIKE PROTEIN 42; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 3.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 86..153
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
SQ SEQUENCE 551 AA; 63348 MW; AF8191AFF61AD85B CRC64;
MDTLWQAVST LMLYLVSCLK CSLVYIQKFL GFEGSLVGVK QNVAKLSRVW GPSNVDPLRN
GSNGSQTEAW KADQESRTYC YHSNGPMVAL QTSTHIFYAD LERLAECSEY FRALSQSCMR
ETEDHLVNLS HVPSRVFHSL LQFCFLHRFS VPDHLIEEHL RVSTYLLVPG FTSRLLLALS
EILTERTCLD YLRLAEELCT DELQETVLVY LSKNLLELPR LNRNLELHLQ QELLLMRSQG
TPQLCCFRKE NLISRDNQET DRARRLFRLE EEDWKWSSVT DLPFTADKWC FTTAVLFNYL
YIIGGYRHHA KRGYEFKMAS FRYNPLTDKW VKTAPLIKHR RHFSAAVCEG HIYAVGGWYL
DSLVTPDSTT GVYTAVERYD PWADSWSFVS SLPLTDFQFT LSLSHDSPLT TSLGTCLYVL
GNIQRTGEKL VLRYDTTQDS WSELYPTLTR ASADIPILHF LGATDKLIVI GGNNFETVVT
SFCVDTQKWG QIRSMEKTAL IGQGTVFNDE VYMSGNQEDV IFRLDLQNLS FSLLPALPVS
TYYESFFHLF F
//
