ID   A0A3B1IJT3_ASTMX        Unreviewed;      1651 AA.
AC   A0A3B1IJT3;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   RecName: Full=SAM domain-containing protein {ECO:0000259|PROSITE:PS50105};
OS   Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Characidae; Astyanax.
OX   NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000030142.1, ECO:0000313|Proteomes:UP000018467};
RN   [1] {ECO:0000313|Proteomes:UP000018467}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA   Jeffery W., Warren W., Wilson R.K.;
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000018467}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX   PubMed=25329095; DOI=10.1038/ncomms6307;
RA   McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA   Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA   Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA   Yoshizawa M., Warren W.C.;
RT   "The cavefish genome reveals candidate genes for eye loss.";
RL   Nat. Commun. 5:5307-5307(2014).
RN   [3] {ECO:0000313|Ensembl:ENSAMXP00000030142.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   Ensembl; ENSAMXT00000033050.1; ENSAMXP00000030142.1; ENSAMXG00000030615.1.
DR   Ensembl; ENSAMXT00000048428.1; ENSAMXP00000045340.1; ENSAMXG00000030615.1.
DR   GeneTree; ENSGT00390000013973; -.
DR   Proteomes; UP000018467; Unassembled WGS sequence.
DR   Bgee; ENSAMXG00000030615; Expressed in intestine and 5 other cell types or tissues.
DR   Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR   InterPro; IPR001660; SAM.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   PANTHER; PTHR16155; DED DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR16155:SF18; STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 9-LIKE; 1.
DR   SMART; SM00454; SAM; 1.
DR   SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR   PROSITE; PS50105; SAM_DOMAIN; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018467}.
FT   DOMAIN          25..71
FT                   /note="SAM"
FT                   /evidence="ECO:0000259|PROSITE:PS50105"
FT   REGION          94..249
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        98..134
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        152..186
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        206..231
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1651 AA;  190553 MW;  5C38A7F336668BCD CRC64;
     MEEHETHFDT AMSHKKEFPR RVEEWTKEQV HQWLSEELKV NQTWADRLYE EDVSGKELIC
     YKAKDLQELG IKHGPAVRII NTLEALVQTH KNEPVLDIQK DTPQTQSEPS GSSTTQCTES
     RHDISVNTAL PKTEQPQQKR KKKKQKSHKK GLGYPDTSTN SEHIGSTNEE PSTNTTTQTT
     ESEGQPKEMP TVMPSPTHKK RKNKTGVSSQ NVPPDITETE PAETTDLPKM QVSNAEEPEI
     KSESKQPQSK HLCSFYPFDQ QSAPHRYIEN YILPPESGPS NLIDPVHEYK FLGRAEDIHI
     MKKKINKEVF RFAAGCMNAR TNGTIHFGVA DSKNSEFSHG EIVGVSVEKT DTIIDHFNQG
     IKQYFEDSAD DAKKCIRQPR FVEVLCCDNT SSSKYVIEVD VVPSHIVVHE KIFYTQTLDE
     ENQWKKCKGK SLFIREGAAT RDIQNIPPKE LTKVIADLKI QDTKRKEAEI KPNRKRKLNQ
     GEKLKSLLID SDYYIIVTNK SHPEQLEHLK FLTTLRLFCV LDFDPDSVGN GTCHNYRKNR
     VANIHTPKQF HGDPGMLTQN LNLYKQTSWV MCNGRLDINT ESDKPLPPNK WLINRAGEVQ
     DMISFLCNPD TLPRQSLVIF LLLSVVESMN DPIFDTFMSF YKNLGGIQNI ISICTTDNAF
     QKWKDFIQIR TEEDLSEQRI FELELSEING SILEKHKQTT ERLLPSFGGS SVVVKQIDED
     SMPALDILYQ NQCENVYAED SEEFKDFRKI TEAEFYRGDK VKWWNFYFSD KTPTKPFIKR
     DKYKQVLKMV RDQTNNPTST CFMVNLFHHP GCGGTTLAMH VMWDLRKEFR CAVLTDNTIT
     KTEVAQQVAY LIKCGKSEKS HKTPVLLLVD DSEDTENTQE LQHCLRKIIG EMDAFVVLLN
     CIRSKNPKEK WKNSVIESQY ITASLSMEEQ NAFEVKLQEL KCNDQPHENF YSFMIMKTNF
     NQEYVTNVAS NILRDVDVGS REAQLLSILA LLNMYVAESS ISVSLCEDFL GIKRRLWGTE
     SVLDKMEPYS CLLIEFQAEE CGVYKAIRFV HQRIAAECVI VLEERNRSPR ADIILNMLHT
     NLFFERGMGR DSLLQSVKSM LITRQRKTEG DEKDTLFSPL IEDIKSGSEG PKKIENILTE
     ASKRFDKDFS IPQALARHYY LNDKNFALAK DWANNAKTIK QNSYTADTVG QVSRRELKYK
     IESKKQEKST YTAEDLNEFL ELAKAAINAF RTAQTLAKKD DVDDTDEKRH WKQNIYNISG
     YMNEIDIAMT VFDIVKGLPL FEENDPMKHE YIRQFFKGKM KVSSIRTAQT DLNDKLMAVL
     KDNEPFLISL KSHVDRAFEF LEEFFTYTRG KGVVDKEKQN KNRNWISDHF KTYISLFCSS
     LEEKQRQRVC KPKLSLHMDI EECRMFLEEN RANNFPRILQ FLEVRKRMIE QIAEKYSFIY
     QNYSAKSLQD KTNHLLTHII LKLNHPASKL AKSQKGLTDL LTDILQEAGL SYQHPEPYYL
     ALLLLWPGNK HVDKHITTYV EKIKRSSQKQ HPYLFRARTP IAHLYLGKGD GLDRLVSKTF
     FDRSFSHVSE RNILWQNAEI FKEAAIKEKL LRVKGIITQG ELYAEYGKLQ IPVRPTYLGG
     IRSGHSTEKV SFYVGFAIDG PLAYDIQYEE T
//