ID A0A3B1IPD5_ASTMX Unreviewed; 804 AA.
AC A0A3B1IPD5;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Hemicentin-1-like {ECO:0000313|Ensembl:ENSAMXP00000031833.1};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000031833.1, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000031833.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B1IPD5; -.
DR Ensembl; ENSAMXT00000057589.1; ENSAMXP00000031833.1; ENSAMXG00000002081.2.
DR GeneTree; ENSGT00940000165428; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000002081; Expressed in zone of skin and 12 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 7.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR11481:SF64; CD166 ANTIGEN-LIKE-RELATED; 1.
DR PANTHER; PTHR11481; IMMUNOGLOBULIN FC RECEPTOR; 1.
DR Pfam; PF13895; Ig_2; 2.
DR Pfam; PF13927; Ig_3; 4.
DR SMART; SM00409; IG; 7.
DR SMART; SM00408; IGc2; 6.
DR SUPFAM; SSF48726; Immunoglobulin; 7.
DR PROSITE; PS50835; IG_LIKE; 7.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..804
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017385822"
FT TRANSMEM 678..700
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..107
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 122..205
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 211..298
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 305..388
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 394..482
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 489..577
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 601..660
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 728..748
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 784..804
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 788..804
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 804 AA; 89962 MW; DA4E2E299D84FAB1 CRC64;
MALIKFILAT AVASMVLSLS NGEDTVGKPT IQQSPSFSMI YTGEQVTLTC KVKEQSSDWK
FYWYKTSEKS KHLNSDTSKS TYTINSAQVS DSGTYMCRVQ KGNSSISPEV NHDLTVKSPP
EPKITQTSGW DRVFPGEKVT LKCVILDKPT DWNYVWLLNN NPVAGSGDTL TISSIKQGQG
GHYTCQTELQ NRPKTQVKSS SFTLTVYAGN PTLLLGKTPS YNVFYTGEQV TLTCEVQEQS
SDWKFYWYKT SEKLNPLNSD SSKSSYTINA VQVSDNGTYV CQVKRGENFQ HEKKNDITVK
GPPEPKVNQK SGWERVFPGE KVTLKCEIPD KSTDWNYVWF LNNNPVAGSG DTLTISSINQ
GQGGHYTCQT ELQNRPKTQV KSSSFTLTVY AGKPTLLLGQ EPAYSVIYTG EQVTLTCKVQ
EQSSGWKYHW YNITDKSKHL NSDTTKSNYT INAAQPSDDG TYVCRVIRGE NDFQHEVNRN
LTVKNPPQPK VSLTSGWDTL FTEEEMTVKC EVSDTSGERW KKTWFKDSQQ IFSHAHVNMT
GNRLSILSAK QSDAGSYTCL TELEKRPKSE ATSTTFSLAV HARAHTVLTL ETSWTDIMSV
DTLTLKCEVQ DETYGWNYTW YKDGVFEVST NEERYSVKAT EETFESEYKC RGNRTERPLY
SSFSEGFRAN KLVLKRKILL AFSGCVVCSI ILLIIGCIVL RVTRKPEKKE AVKEDLFISM
TNSKTETTSP LQEYLKENGP PVDKGEHNES TASAAMDEIK DAVVDVDVLP AKNTGGFTSF
QVEKSAGNGL KSEEHDESAA LLKK
//
