ID A0A3B1IW22_ASTMX Unreviewed; 260 AA.
AC A0A3B1IW22;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Somatomedin-B and thrombospondin type-1 domain-containing protein-like {ECO:0000313|Ensembl:ENSAMXP00000033289.1};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000033289.1, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000033289.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B1IW22; -.
DR STRING; 7994.ENSAMXP00000033289; -.
DR Ensembl; ENSAMXT00000037603.1; ENSAMXP00000033289.1; ENSAMXG00000039755.1.
DR GeneTree; ENSGT00390000008325; -.
DR InParanoid; A0A3B1IW22; -.
DR OrthoDB; 2872519at2759; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000039755; Expressed in camera-type eye and 9 other cell types or tissues.
DR Gene3D; 4.10.410.20; -; 1.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 1.
DR InterPro; IPR039942; SBSPO.
DR InterPro; IPR001212; Somatomedin_B_dom.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR InterPro; IPR044004; TSP1_spondin_dom.
DR PANTHER; PTHR20920; RPE-SPONDIN; 1.
DR PANTHER; PTHR20920:SF7; SMB DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01033; Somatomedin_B; 1.
DR Pfam; PF19028; TSP1_spondin; 1.
DR SMART; SM00201; SO; 1.
DR SMART; SM00209; TSP1; 1.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 1.
DR PROSITE; PS00524; SMB_1; 1.
DR PROSITE; PS50958; SMB_2; 1.
DR PROSITE; PS50092; TSP1; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..260
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017378997"
FT DOMAIN 35..80
FT /note="SMB"
FT /evidence="ECO:0000259|PROSITE:PS50958"
SQ SEQUENCE 260 AA; 28460 MW; 2AB6E4E6F71A0DE7 CRC64;
MVGGCAALCG ALCGALLCVS GLWLPGARAG CADRESPACC TGRNNECAEL NRRKTACYCD
SYCEKTGDCC EDYRQVCQIS AAIDCEVGEW GVWSPCSSVC GAGTTERSRQ VTTPPRNGGS
PCPDLKQRRG CLAHLDTCST AKEVAKILPD SFKRNFKDPW RRPHMLIKEE RKSYCVNMRV
KQVSAACRMK VWSSQMARER SVCVECQSDA MAADNRCRGD GLQSIRTFWA AASAPGCLGS
WIRESWSESC YCPAHSLLFI
//
