ID A0A3B1J6U3_ASTMX Unreviewed; 240 AA.
AC A0A3B1J6U3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=GAIN domain-containing protein {ECO:0000259|Pfam:PF16489};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000037958.1, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000037958.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3B1J6U3; -.
DR STRING; 7994.ENSAMXP00000037958; -.
DR Ensembl; ENSAMXT00000056862.1; ENSAMXP00000037958.1; ENSAMXG00000041123.1.
DR GeneTree; ENSGT00940000160103; -.
DR InParanoid; A0A3B1J6U3; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000041123; Expressed in brain and 4 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0016525; P:negative regulation of angiogenesis; IEA:InterPro.
DR Gene3D; 1.25.40.610; -; 1.
DR Gene3D; 2.60.220.50; -; 1.
DR InterPro; IPR032471; GAIN_dom_N.
DR InterPro; IPR046338; GAIN_dom_sf.
DR InterPro; IPR008077; GPCR_2_brain_angio_inhib.
DR PANTHER; PTHR10239:SF32; ADHESION G PROTEIN-COUPLED RECEPTOR B2; 1.
DR PANTHER; PTHR10239; ISTHMIN-2; 1.
DR Pfam; PF16489; GAIN; 1.
DR PRINTS; PR01694; BAIPRECURSOR.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018467}.
FT DOMAIN 9..206
FT /note="GAIN"
FT /evidence="ECO:0000259|Pfam:PF16489"
SQ SEQUENCE 240 AA; 27196 MW; 8420D805E32B64CE CRC64;
MRTLAGEGMS QIVRSLLELM SRRSYYSGDL LFSVEILRNV TDTFKRATYI PAPDDVQKFF
QIVSLMLDME NLEKWEDAHQ VSPGAVLLMR VVEDFIHLIG EAQKPFQSFL VVTTNLIITI
QREPVSAVSS DINFPTKGRR GMKDWARSAE DKLFIPKEVF TLSSDEMPSS SGARGGNEES
DEASYFVIGA ILYRTLNFIL PAPKPPAVPL GKYQKLVGIF LLHLILRKKA REVWQKKINK
//
