ID A0A3B1JJ82_ASTMX Unreviewed; 702 AA.
AC A0A3B1JJ82;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=RAB, member RAS oncogene family-like 6b {ECO:0000313|Ensembl:ENSAMXP00000041905.1};
GN Name=RABL6 {ECO:0000313|Ensembl:ENSAMXP00000041905.1};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000041905.1, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000041905.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A3B1JJ82; -.
DR STRING; 7994.ENSAMXP00000041905; -.
DR Ensembl; ENSAMXT00000031835.1; ENSAMXP00000041905.1; ENSAMXG00000038771.1.
DR GeneTree; ENSGT00390000016002; -.
DR InParanoid; A0A3B1JJ82; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000038771; Expressed in camera-type eye and 14 other cell types or tissues.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR040385; RABL6.
DR PANTHER; PTHR14932:SF1; RAB-LIKE PROTEIN 6; 1.
DR PANTHER; PTHR14932; RAS GTPASE-RELATED; 1.
DR Pfam; PF08477; Roc; 1.
DR PRINTS; PR01217; PRICHEXTENSN.
DR SMART; SM00175; RAB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018467}.
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 275..551
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 582..702
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 280..314
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..348
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 467..490
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 491..522
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 614..632
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 702 AA; 76109 MW; A2B8C0DEC4EEE923 CRC64;
MLSALKKLVG SEPPVPPREK NIPAGLQSMN QSLQRRFAKE SNTTIVIRGD RNTGKSTLWQ
RLQGGKFQEE YIPTQEIQVT SIHWNYKTTD DVVKVEVWDV VDKGELKKLI SVSGVINTAE
SEIALDAEFL DVYKNCNGVI MMFDITKQWT YSYILRELPR VPTHVPVCVL GNHRDMGEHR
VILPDDIRDF ISGMNRPLGS SYIHYAESSM KNGFGLKYLH RFFNIPFLQL QRETLLRQLE
TNQLDMDATL EELTVQQETE DQNYDIFLEM MDSRSKGCVS PGADNGQSPS SGSQSPVVAA
GGSSTGSSSP GTPQQPAGPE RPAPSPAPPT AAPAPAPSPA PAPSPVPQPQ KRSFISRLFG
SSPAPDPLAP EPEAESGAPE APPTVQSVDD FVPDDGLDKS FLEDSMSSPP PPAGPDIDSD
GEGGGGGGNP MVAGYQIDLD LDDSDLRAPV PDVTLSSDEE VGGAPPEKPK PTEPNILIPT
PAPSTHTPAP STHTPAPSTH TPAPSTHTPA PSTHTQVHTP APAAGPQVQH CKKKPVPGDS
SDTDPEEPAA QMLSFIMDDP DFESEEELVQ KVNKDFPVRV DLSDISDEEL VPAKVSEPQK
VPVRSFKQKN DSDLFGLGFE EKSLKNRDSS EEQEGQSSNQ LLKKSSKKKH KHKKKEEEAG
TGEEKKKKKS RSKKSGELDD LEAFLAGGAG SARREEGDYE EL
//
