ID A0A3B1K0S6_ASTMX Unreviewed; 660 AA.
AC A0A3B1K0S6;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Kelch-like protein 31 {ECO:0000313|Ensembl:ENSAMXP00000048277.1};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000048277.1, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000048277.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B1K0S6; -.
DR STRING; 7994.ENSAMXP00000048277; -.
DR Ensembl; ENSAMXT00000055360.1; ENSAMXP00000048277.1; ENSAMXG00000030505.1.
DR GeneTree; ENSGT00940000166197; -.
DR InParanoid; A0A3B1K0S6; -.
DR OrthoDB; 5472491at2759; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000030505; Expressed in muscle tissue and 6 other cell types or tissues.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR45632:SF18; KELCH-LIKE PROTEIN 31; 1.
DR PANTHER; PTHR45632; LD33804P; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 3.
DR Pfam; PF13415; Kelch_3; 1.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 5.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 92..156
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REGION 641..660
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 660 AA; 73204 MW; DE8567EBE9E08C3F CRC64;
MAPKKKSPRP KKATPEPVQV NNEVVVPEPG VKKLELPLNV EQMNRLNGIP LPPPVIRPGE
RGFGLGGEMT RPLHGSALLE ELSRMRQERF LTDLELACKT KAFDVHKLVM SSVSQYLREV
LAKDPGLKRL ELPTLSPLGL ANVITFAYLG RVHMSLYTIG CTVSAASTLQ IPHLLQMCMD
FLMAELNVHT CVYVWNIGTA FGLDPVRDAA RRFVLENFSQ FSETPQFTQL TLEQIIAFLQ
DDNLMLSSEV TTFQVAMKWL DFDPNRAAHA SELLSHVRFE TIPASELVSE IQPAARMMLD
PQCHRLLVDA MNYHLLPYQQ NTLQSRRTKV RGSQTTLLTI GGRPSLTERA LSREVLWRDP
REGAATWRHL SQLPAKSFNQ CVAVMDGFLY VAGGEDQNDA RNQAKHAVST LCRYDPRFNT
WLHLCSMRQR RTHFSLVATG GRLLAIGGRN TDGLLATIES YLPSTNSWQL RAPMEMPRCC
HASAVLPSGD VLVTGGYINC AYSRSVARYS LESDSWSEQA QLEMPRGWHC SATLGGKVYV
VGGSQLGPAG ERVDVLTTEV FCPESGQWSR AASLPLGVST AGLSPLGNHL YLLGGWNEAQ
KRYKSAVQRY DPGTDTWALA EDLPEPTVGV SCCALALPPR HATRRHRNTP SHEEQSSITA
//
