ID A0A3B1K214_ASTMX Unreviewed; 281 AA.
AC A0A3B1K214;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Protein Mpv17 {ECO:0000256|ARBA:ARBA00040811};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000048533.1, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000048533.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the peroxisomal membrane protein PXMP2/4 family.
CC {ECO:0000256|ARBA:ARBA00006824, ECO:0000256|RuleBase:RU363053}.
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DR AlphaFoldDB; A0A3B1K214; -.
DR STRING; 7994.ENSAMXP00000048533; -.
DR Ensembl; ENSAMXT00000040765.1; ENSAMXP00000048533.1; ENSAMXG00000008148.2.
DR GeneTree; ENSGT00940000160891; -.
DR InParanoid; A0A3B1K214; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000008148; Expressed in ovary and 14 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007248; Mpv17_PMP22.
DR PANTHER; PTHR11266; PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17; 1.
DR PANTHER; PTHR11266:SF17; PROTEIN MPV17; 1.
DR Pfam; PF04117; Mpv17_PMP22; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU363053};
KW Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW Transmembrane {ECO:0000256|RuleBase:RU363053};
KW Transmembrane helix {ECO:0000256|RuleBase:RU363053}.
FT TRANSMEM 58..76
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363053"
FT TRANSMEM 159..178
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363053"
FT TRANSMEM 199..220
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363053"
FT TRANSMEM 232..253
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363053"
SQ SEQUENCE 281 AA; 31777 MW; D278503E2AAA3C10 CRC64;
MSYLYVCSLK CVKRLKSSRG PNTFSRPCRC CLRHISLNSQ FSLINFLRKP IFKTKLHSGY
IFGVPLFFIV INYVLFYVVD ALMSLASSNF CIQIFTSFCV SEKSMAGLWR SYQLLMARRP
WTVQILTAGS LVGVGDVISQ QLIERRGLSN HCVKRTAKMM SIGFFFVGPV VGGWYKVLDQ
LITGGTKQAA LKKMLVDQVC FAPCFLATFL GISGTLNGLT VEENVAKLQR DYVDALISNY
YLWPAVQIAN FYFIPLHHRL AVVQVVAVVW NSYLSWKANK L
//
