ID A0A3B1K7H2_ASTMX Unreviewed; 326 AA.
AC A0A3B1K7H2;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=SRCR domain-containing protein {ECO:0000259|PROSITE:PS50287};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000050622.1, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000050622.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
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DR AlphaFoldDB; A0A3B1K7H2; -.
DR Ensembl; ENSAMXT00000031727.1; ENSAMXP00000050622.1; ENSAMXG00000039257.1.
DR GeneTree; ENSGT00950000183145; -.
DR InParanoid; A0A3B1K7H2; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR Gene3D; 3.10.250.10; SRCR-like domain; 3.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR48071; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48071:SF15; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00530; SRCR; 3.
DR PRINTS; PR00258; SPERACTRCPTR.
DR SMART; SM00202; SR; 3.
DR SUPFAM; SSF56487; SRCR-like; 3.
DR PROSITE; PS00420; SRCR_1; 3.
DR PROSITE; PS50287; SRCR_2; 3.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196}; Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..326
FT /note="SRCR domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017250773"
FT DOMAIN 11..96
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 106..206
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 213..313
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DISULFID 131..195
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 144..205
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 175..185
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 238..302
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 251..312
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 282..292
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ SEQUENCE 326 AA; 34392 MW; BA3B0A8B72E089CD CRC64;
LNLLFLLAFP IRLVSGSGLC DGRVEISIND QWGTVCDDHW DINNGDVVCR QMGCGRAVSA
PHVSSFGQEV GSNNLMTLGL GVNNCDHSKD AGVFTCTSPN PLYISIRLVN GSGLCDGRVE
ISINDQWGTV CDDLWDINDG DVVCRQMGCG RAVSPAQSSS FGPGSGTIYL DDVVCSGNER
SLTKCSHRGL GVNNCDHSKD AGVVCSGKVP FVIRLVSGSG RCDGRVEISI NDQWGTVCDD
LWDINDGDVV CRQMGCGRAI SAPQSSRFGP GSGSIYLDDV VCSGSERSLT KCSHRGIGVN
NCDHSKDAGV VCSGKVPFLV SVIAVC
//
