ID   A0A3B1KET5_ASTMX        Unreviewed;       705 AA.
AC   A0A3B1KET5;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Zinc finger, C2HC-type containing 1C {ECO:0008006|Google:ProtNLM};
OS   Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC   Characoidei; Characidae; Astyanax.
OX   NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000052204.1, ECO:0000313|Proteomes:UP000018467};
RN   [1] {ECO:0000313|Proteomes:UP000018467}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA   Jeffery W., Warren W., Wilson R.K.;
RL   Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000018467}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX   PubMed=25329095; DOI=10.1038/ncomms6307;
RA   McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA   Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA   Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA   Yoshizawa M., Warren W.C.;
RT   "The cavefish genome reveals candidate genes for eye loss.";
RL   Nat. Commun. 5:5307-5307(2014).
RN   [3] {ECO:0000313|Ensembl:ENSAMXP00000052204.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the ZC2HC1 family.
CC       {ECO:0000256|ARBA:ARBA00010843}.
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DR   AlphaFoldDB; A0A3B1KET5; -.
DR   STRING; 7994.ENSAMXP00000052204; -.
DR   Ensembl; ENSAMXT00000054229.1; ENSAMXP00000052204.1; ENSAMXG00000040113.1.
DR   GeneTree; ENSGT00940000160947; -.
DR   InParanoid; A0A3B1KET5; -.
DR   Proteomes; UP000018467; Unassembled WGS sequence.
DR   Bgee; ENSAMXG00000040113; Expressed in testis and 12 other cell types or tissues.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR   InterPro; IPR026104; ZNF_C2HC_dom_1C.
DR   PANTHER; PTHR14649; ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1C; 1.
DR   PANTHER; PTHR14649:SF1; ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1C; 1.
DR   Pfam; PF13913; zf-C2HC_2; 2.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           17..705
FT                   /note="Zinc finger, C2HC-type containing 1C"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5017207024"
FT   REGION          202..245
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          286..362
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          441..464
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          527..547
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          681..705
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        223..245
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   705 AA;  83764 MW;  D1B90CD6F460A4CD CRC64;
     MFICFYTLLI SVLVNCKTFI FNPVTTSPIS QRLIYKLFCF FFFLDIKCSI GIMPHLHISH
     SHPAHLHFLG KDVILEKLPP LQSDDKTAQD LFSTSDSQSR DRKKRMTAAL KDWDQDYSHY
     KHWQNIDSVQ RTYSSAPTRR RMDSDGDDDF LLEKSEKDIV FPMKPVCHKR AFCLNNCQAG
     DYYFKQKETS YQNRPDYLEV DRRRVKQVSN RRQVNMNPSK PEPFDTESHH QPSRKRGEAK
     SNSAREYQAL REDQYMLPES QNSLAKEIQR KEVILQEKLM KTGEKLKKIQ LRTRSGDKDK
     REQRNENMEK QEKHLHLTEK GNWDWESGRE RAIAGRRRDE GQREKPRDWG REDRDDRERR
     EKHEIKTDED YRERRREGIE REYRMRNTQR TSDYKIMSKE WDNHEVRTTQ WKTVRVEKDN
     IIKRERAVEW GRNELREWDS RDRQGRVDDD RQRRGERVKS KRDLENEYQK KQWNVLDAFM
     SNSHDKVKAS SRHDQTNRFT ADQHPAQVRL QQQQHSQRAV EKAINSFRKG PPKAPSTEEA
     VAQSPRLNQI GTRLQQVELS PEMSLDATGQ LVPCEICNRC FAEERLEKHI RICEKLQQSK
     RKTFDSAQFR AKGTELEKFM KTNIQRKAPE PKKNNWRQKH EALIHNLRQA RAPAPGGFSP
     KPSLDVNPDY VSCPHCSRRF APGPAERHIP KCQNIKSKPP PPRHR
//