ID A0A3B1KJ65_ASTMX Unreviewed; 464 AA.
AC A0A3B1KJ65;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=SRCR domain-containing protein {ECO:0000259|PROSITE:PS50287};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000053881.1, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000053881.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00196}.
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DR AlphaFoldDB; A0A3B1KJ65; -.
DR Ensembl; ENSAMXT00000049398.1; ENSAMXP00000053881.1; ENSAMXG00000030886.1.
DR GeneTree; ENSGT00950000183145; -.
DR InParanoid; A0A3B1KJ65; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000030886; Expressed in intestine and 2 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR Gene3D; 3.10.250.10; SRCR-like domain; 4.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR48071; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48071:SF15; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00530; SRCR; 4.
DR PRINTS; PR00258; SPERACTRCPTR.
DR SMART; SM00202; SR; 4.
DR SUPFAM; SSF56487; SRCR-like; 4.
DR PROSITE; PS00420; SRCR_1; 3.
DR PROSITE; PS50287; SRCR_2; 4.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196}; Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..464
FT /note="SRCR domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017387474"
FT DOMAIN 25..125
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 136..236
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 245..341
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 343..443
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DISULFID 50..114
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 63..124
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 94..104
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 161..225
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 174..235
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 205..215
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 313..323
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 368..432
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 381..442
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 412..422
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ SEQUENCE 464 AA; 50023 MW; 1BBA0E4E0DCCE170 CRC64;
LSFVKFHVFQ IKLHSIFILI AELNVRLVNG TGSCSGRVEV YYKGQWGTVC DDGWDINDAD
VVCRQMGCGG ALSVHSSAHF GKGTGLIILD NIYCFGNESS LTECRHSGIG NHDCNHGEDA
GVACSGEEHC SILGYIRLVN GTGFCNGRVE IYHDGQWGTV CDDGWDINDA DVVCRQMGCG
RALNTTHSAH FGEGNGPVLL DDVECAGHES HLISCSHKEV GKINCSHSED AGVICSGKIP
FLVSVRLLNG TGSCSGRVEV YYKDQWGTVC DDDWDINDAD VVCRQMGCGR AVGVHSNDYF
GQGTRAVIKD VRCYGTERFI EACSSDGFPK YSCNHAGVTC SEIRLVNGTG NCDGRVEIYH
DGQWGTVCGD NWDMKDAEVV CRQVECGRAL NSTHSAHFGE GNGPVLLDDV GCSGQENNLL
SCSHGGLGIT NCSHSEDAGV VCSGKNIESF KSFLCLDYTS NYRF
//
