ID A0A3B1KKB3_ASTMX Unreviewed; 1160 AA.
AC A0A3B1KKB3;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=SRCR domain-containing protein {ECO:0000259|PROSITE:PS50287};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000054271.1, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000054271.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A3B1KKB3; -.
DR Ensembl; ENSAMXT00000046046.1; ENSAMXP00000054271.1; ENSAMXG00000042347.1.
DR GeneTree; ENSGT00940000162108; -.
DR InParanoid; A0A3B1KKB3; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR Gene3D; 3.10.250.10; SRCR-like domain; 10.
DR InterPro; IPR001190; SRCR.
DR InterPro; IPR017448; SRCR-like_dom.
DR InterPro; IPR036772; SRCR-like_dom_sf.
DR PANTHER; PTHR48071; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR48071:SF15; SRCR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00530; SRCR; 10.
DR PRINTS; PR00258; SPERACTRCPTR.
DR SMART; SM00202; SR; 10.
DR SUPFAM; SSF56487; SRCR-like; 10.
DR PROSITE; PS00420; SRCR_1; 9.
DR PROSITE; PS50287; SRCR_2; 10.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00196}; Reference proteome {ECO:0000313|Proteomes:UP000018467}.
FT DOMAIN 1..98
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 101..201
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 204..304
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 321..421
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 470..570
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 575..675
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 685..763
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 788..888
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 891..991
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DOMAIN 1005..1105
FT /note="SRCR"
FT /evidence="ECO:0000259|PROSITE:PS50287"
FT DISULFID 23..87
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 36..97
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 67..77
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 126..190
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 139..200
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 170..180
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 229..293
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 242..303
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 273..283
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 346..410
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 359..420
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 390..400
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 495..559
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 508..569
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 539..549
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 600..664
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 613..674
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 644..654
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 688..752
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 701..762
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 732..742
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 813..877
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 826..887
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 857..867
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 916..980
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 929..990
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 960..970
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1030..1094
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1043..1104
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
FT DISULFID 1074..1084
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00196"
SQ SEQUENCE 1160 AA; 122650 MW; 24476A9F53D74B3D CRC64;
IYGSGLCDGR VEISINDQWG TVCDDLWDIN DGDVVCRQMG CGRAVSTPQS SRFGPGSGSI
YLDDVVCSGS ERSLTKCSHS GLGVNNCDHS KDAGVVCSGK IRLVSGSGLC DGRVEISIND
QWGTVCDDLW DINDGDVVCR QMGCGQTVSA PQSSRFGPGS GSIYLDDVVC SGSERSLTKC
SHRGLGVNNC DHSKDAGVVC SENIRLVNGS ALCDGRVEIS INDQWGTVCD DLWDINDGDV
VCRQMGCGRA VSVPQSSRFG PGSGSIYLDD VVCSGSERSL TKCSHRGLGV NNCDHSKDAG
VVCSGKVPFL ISNAPYRRYT YMLVSGSGLC DGRVEISIND QWGTVCDDLW DINDGDVVCR
QMGCGRAVSA PQGSRFGPGS GSIFLDDVVC SGSERSLTKC SHRGLGVNNC DHSKDAGVVC
SDLIEGDVSS SMRICLRDTA ISLSTPLHTL KCFWFSEPFC TFSHVQLENI RLVNGSGRCD
GRVEISINDQ WGTVCDDLWD INDGDVVCRQ MGCGRAVSAP QGSRFGPGSG SIYLDDVGCS
GSERSLTKCS HSGLGLNNCD HSKDAGVVCS GKVYHVLIYG SGLCDGRVEI SINDQWGTVC
DDLWDINDGD VVCRQMGCGR AVSAPQSSRF GPGSGSIYLD DVVCSGSERS LTKCSHRGLG
VNNCDHSKDA GVVCSEKIRL VSGSGLLCDD LWDINDGDVV CRQMGCGRAV SVPQSSRFGP
GSGSIYLDDV VCSGSERSLT KCSHRGLGVN NCDHSKDAGV VCSGKVPFLI SNAVSPSSGL
YCADSEKIRL VSGSGRCDGR VEISINDQWG TVCDDGWDIN DGDVVCRQMG CGQAVSARGS
AYFGQGSGPI HLDEVGCSGH ESTLTNCSNK GIGVHDCDHH EDAGVVCSEN IRLVKGHYRC
EGRVEVYLNN QWGTVCDDGW DINDGDVVCR QVGCGRAVIA RSSAYFGQGS GTIYLDDVGC
SGSETTLTDC SNRGIGVHNC GHQEDAGVVC SGEKSLLEKA YTQLIRLVSG SGLCDGRVEI
SINDQWGTVC DDLWDINDGD VVCRQMGCGR AVSASQSSRF GPGSGTIYLD DVVCSGSERS
LTKCSHRGLG VNNCTHSKDA GVVCSGKVPF LISIEAQGKT QDMLEGLCLG RPGNASGFQT
SPREVWVSLL RLLPPRPNPG
//
