ID   A0A3B3B5Q0_ORYME        Unreviewed;       494 AA.
AC   A0A3B3B5Q0;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Inositol polyphosphate-5-phosphatase Jb {ECO:0000313|Ensembl:ENSOMEP00000000895.1};
OS   Oryzias melastigma (Marine medaka).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000000895.1, ECO:0000313|Proteomes:UP000261560};
RN   [1] {ECO:0000313|Ensembl:ENSOMEP00000000895.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase
CC       type II family. {ECO:0000256|ARBA:ARBA00005910}.
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DR   AlphaFoldDB; A0A3B3B5Q0; -.
DR   STRING; 30732.ENSOMEP00000000895; -.
DR   PaxDb; 30732-ENSOMEP00000000895; -.
DR   Ensembl; ENSOMET00000015103.1; ENSOMEP00000000895.1; ENSOMEG00000001787.1.
DR   GeneTree; ENSGT00940000156855; -.
DR   OMA; MYIILQE; -.
DR   Proteomes; UP000261560; Unplaced.
DR   GO; GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR   CDD; cd09094; INPP5c_INPP5J-like; 1.
DR   Gene3D; 2.60.40.2840; -; 1.
DR   Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR   InterPro; IPR046985; IP5.
DR   InterPro; IPR000300; IPPc.
DR   InterPro; IPR041611; SKICH.
DR   PANTHER; PTHR11200; INOSITOL 5-PHOSPHATASE; 1.
DR   PANTHER; PTHR11200:SF127; PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 5-PHOSPHATASE A; 1.
DR   Pfam; PF03372; Exo_endo_phos; 1.
DR   Pfam; PF17751; SKICH; 1.
DR   SMART; SM00128; IPPc; 1.
DR   SUPFAM; SSF56219; DNase I-like; 1.
PE   3: Inferred from homology;
FT   DOMAIN          62..380
FT                   /note="Inositol polyphosphate-related phosphatase"
FT                   /evidence="ECO:0000259|SMART:SM00128"
FT   REGION          1..61
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        21..46
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   494 AA;  55847 MW;  7FA92475E260054A CRC64;
     MNPNADSKSG QPAVPHRPRR PQRSPRVESS VDISEPKTEP VPPADKEEST PDGIAASRPK
     PSRPAVHIIT WNVGSAEPPD DITALLGLNV GDGNTDMYII GLQEVNSMIN KRLKDVLFTD
     QWSEVCMERL SPFGYVTSQR MQGLLLLVFA KYFHLPFLRG VQTEATRTGL GGYWGNKGGV
     SARMSVFGHT VCFVNCHLPA HMENSDQRME DFESILQQQQ FEGQAATGVL DHDVVFWFGD
     LNFRIDDLEI QVVKSAIDNN KFSALLEKDQ LNMAKDSETV LEGFHEGPLK FPPTYKFDVG
     TNTYDTSGKK RKPAWTDRIL WRLRATAPAA QSSGKRGSFS GLTSGTKVTQ HFYQSHMEYT
     ISDHKPVSSI FTLQFPYKLD IPLVTIIVED EWNSVAEAKV IFKVAPKYSR SSWDWIGLYK
     VGFKHPKDYV GYVWAKQEEA DFLRQEHEVN PMRAEFCSRI FFVTFDKCLS NSFPGNLYRG
     RIAQRLRGLY FGLL
//