ID A0A3B3B6Y8_ORYME Unreviewed; 1391 AA.
AC A0A3B3B6Y8;
DT 05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Lymphoid-restricted membrane protein-like {ECO:0000313|Ensembl:ENSOMEP00000000803.1};
OS Oryzias melastigma (Marine medaka).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000000803.1, ECO:0000313|Proteomes:UP000261560};
RN [1] {ECO:0000313|Ensembl:ENSOMEP00000000803.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
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DR Ensembl; ENSOMET00000015276.1; ENSOMEP00000000803.1; ENSOMEG00000001741.1.
DR GeneTree; ENSGT00530000063722; -.
DR Proteomes; UP000261560; Unplaced.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR028168; KASH5_coiled-coil.
DR InterPro; IPR039508; KASH5_EF-hand-like_dom.
DR InterPro; IPR008677; MRVI1.
DR PANTHER; PTHR15352:SF3; INOSITOL 1,4,5-TRIPHOSPHATE RECEPTOR ASSOCIATED 2-RELATED; 1.
DR PANTHER; PTHR15352; LYMPHOID-RESTRICTED MEMBRANE PROTEIN, JAW1; 1.
DR Pfam; PF14658; EF-hand_9; 1.
DR Pfam; PF14662; KASH_CCD; 1.
DR Pfam; PF05781; MRVI1; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1333..1354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 239..303
FT /note="Protein KASH5 EF-hand-like"
FT /evidence="ECO:0000259|Pfam:PF14658"
FT DOMAIN 357..545
FT /note="KASH5-like coiled-coil"
FT /evidence="ECO:0000259|Pfam:PF14662"
FT REGION 26..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 71..106
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 130..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 733..753
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 772..1092
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1232..1314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 365..493
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 705..732
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 80..106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 772..793
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 867..881
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 892..933
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 937..969
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1003..1032
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1033..1092
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1235..1249
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1252..1274
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1391 AA; 154450 MW; 4E914CB909F3A43C CRC64;
MDCCTPPPPR RHNPVDSICR KLQTIQWRGD REPNSPFQIP KLSSSSYDSP QCSLRSNLEA
ILKKGAFHRD QRGTGARMGM PSSVASQRSA AGHYTPTRHS STPANVTYSI TSTLGERHRG
EGRDLGQTWQ KYHSTPSTQP KDSPYFTFTR GPQSGQSDSD GPSSSPHLSR TFTPSRSTFS
YNLNFCSADG ADAAESELPY PALVVKRLSM GEGGTSVASE NGTAMAEISL ICEENLLDTI
FHACDTQRRG KVFVSHIVDY LRHTTSRSSE DSGLEELCNM LDPERKDVSI DLDTYHAVMR
EWIDDCRNNG QEESEDMTQE DSVKVRDGVP DRKSMLLNMT SGSLEAFGGE ASRAEFETSE
LVYCVADLQM GNQKLQEEVR KLKQVVEGME ESNQKLAEEN EELRTQARIN QQMAQKEKLL
KEEVEEMKAT LSCTEEGRAR ASAHSKHVER ENQSLMAKIS SLEDENFKIT METDELQKRI
KELCDLNADL QVQIHAIDAI LNEKESVIVE RDRQVEELKA AVEEYSAITE LLRMEKSKLE
NQMQMILPDL AGSSLSLCGA YRLNQSSSGS LQTELALAQS PLEAPHGVDH LSAVMSQASP
LDETLDREVL LLLQGPDPEH MALEFRNLLN KLKKDLEEES CSVVSTVRGF LGSDVEPRLQ
TVRAELDARR ADWADRLDQL AQYTDSLEKE LIKMASNMRR SRTEILHLSV RVQEQENQKR
QLREDLELLK APQDAREVSC QTPEPEEEPG EDLDWEEEFA LQDFLKNELA ERNCGAPERR
EAAASLPDRC DEEETWTVES EAKEDGGGRD ISTPLSAVFL ATPTAHPSVA DGRDAQPEEN
HQPLQKAAAA PLDAHSQAVS AKHPEADALP DLSHSEKSDE VCGGAESPSC GPEPAVSSSS
EQEQTITPAD MLLPNTTATD PEDTLSLTES SLLTCEELGG EEEKSEAGSS AADMRRHKSL
IRDGSAERPA AEDGSCLLPV LVEEEESAQD TAAQAEDVTR LPRSENLVSN SSSPTATSIT
ADSPTGRRGS RATSDPRQPE TDQEFVRNMS AAEEQKGQDE RSESSRASER DSETSVLSDT
SEAFREERNS LSPNDKEIEA EFQRLSLGFK CDMFTLEKRL KLEQRSRDLA EENIRKEVSS
CQGLLQALTP LCEDDTQSME IIQRLQKNLD ILIQSTNRVS SRSEMLGAIH QENRIGKAVE
VMIQHVENLK RTYTKEHAEL LELREALMQN ERSFGSQTER DDFRGRKQTS NNKTRRFSTT
AIPYSGYRQL DMVKTQETSE GDMEKLNRRS PCPSPPSSPT ASDQTMVQPL SHDPLDSRRV
SAAAVAARAS RGLWLWLAIV VVLAGLLALL ACLVMQPAAD AAPVGTGDSW MTIQQLLWPY
TGLRHNAQPP V
//
