ID   A0A3B3B996_ORYME        Unreviewed;       533 AA.
AC   A0A3B3B996;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=Tripartite motif-containing protein 66 {ECO:0000313|EMBL:KAF6721531.1};
GN   ORFNames=FQA47_002169 {ECO:0000313|EMBL:KAF6721531.1};
OS   Oryzias melastigma (Marine medaka).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=30732 {ECO:0000313|Ensembl:ENSOMEP00000002115.1, ECO:0000313|Proteomes:UP000261560};
RN   [1] {ECO:0000313|Ensembl:ENSOMEP00000002115.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2023) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:KAF6721531.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Bigg-433 {ECO:0000313|EMBL:KAF6721531.1};
RX   PubMed=32938378;
RA   Liang P., Saqib H.S.A., Ni X., Shen Y.;
RT   "Long-read sequencing and de novo genome assembly of marine medaka (Oryzias
RT   melastigma).";
RL   BMC Genomics 21:0-0(0).
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DR   EMBL; WKFB01000489; KAF6721531.1; -; Genomic_DNA.
DR   STRING; 30732.ENSOMEP00000002115; -.
DR   PaxDb; 30732-ENSOMEP00000002115; -.
DR   Ensembl; ENSOMET00000013045.1; ENSOMEP00000002115.1; ENSOMEG00000003029.1.
DR   GeneTree; ENSGT00940000165144; -.
DR   OMA; SWTEPYC; -.
DR   OrthoDB; 56754at2759; -.
DR   Proteomes; UP000261560; Unplaced.
DR   Proteomes; UP000646548; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd05502; Bromo_tif1_like; 1.
DR   Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR001487; Bromodomain.
DR   InterPro; IPR036427; Bromodomain-like_sf.
DR   InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR001965; Znf_PHD.
DR   InterPro; IPR019787; Znf_PHD-finger.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR45915; TRANSCRIPTION INTERMEDIARY FACTOR; 1.
DR   PANTHER; PTHR45915:SF7; TRIPARTITE MOTIF-CONTAINING PROTEIN 66; 1.
DR   Pfam; PF00439; Bromodomain; 1.
DR   Pfam; PF00628; PHD; 1.
DR   PRINTS; PR00503; BROMODOMAIN.
DR   SMART; SM00297; BROMO; 1.
DR   SMART; SM00249; PHD; 1.
DR   SUPFAM; SSF47370; Bromodomain; 1.
DR   SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR   PROSITE; PS50014; BROMODOMAIN_2; 1.
DR   PROSITE; PS01359; ZF_PHD_1; 1.
DR   PROSITE; PS50016; ZF_PHD_2; 1.
PE   4: Predicted;
KW   Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000646548};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00146}.
FT   DOMAIN          313..360
FT                   /note="PHD-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50016"
FT   DOMAIN          400..472
FT                   /note="Bromo"
FT                   /evidence="ECO:0000259|PROSITE:PS50014"
FT   REGION          1..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          67..87
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          173..225
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        179..208
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   533 AA;  59876 MW;  0310E781F5F3D977 CRC64;
     MADLTHRYHG NFPPRRATLY PRGEGGLARQ TPETVSPETG PDMAAVAEVG ALSTDQMRGF
     GPCEMEEPNC PEKSMNPTSR GWEKPPDRSV KGLLRTIRIH PEAQRILGKS SIAVVTLERL
     NFQSVSLWSL QPVVSLQRLP VQAHAEPLME ETTTSPEQPV EQNGFSQEEA EMFEISETST
     ESDHLSQAET AAASWTEPVC SDSASSEEPE QDSGFDCDSN PDLPFILFDS GSDGGESDSE
     TFYLDPDAKQ AVVMELEPQT QEAPDTRLQL EDEAEGKCEA DGVEVEHGEE QKPELCCAFE
     LQLEAAGGAV ESEDFCAVCL NGGELLCCDR CPKVFHVSCH IPPLTSFPLG DWVCTLCRTD
     QEPMETCGCE DTPSSTQVRA PYTLSEHNQR RCEKLCLLLY CHELSAPFHE PVSPLAQNYY
     QIIKRPIDLS VIRRKLDKSN TLHYFTPEQF VDDVLLMFKN CATFNYPDSE VAQAGRSLEE
     FFLIKLKEVF PDQTFPSAAQ DRTDRARLHW LSRKRRENYR RKRHVFSGKK YYL
//